PubMed Health⌕ Search

Biomedical subjects

R E Koehler

Publications and source records attributed to R E Koehler.

At least 91 records · Page 5Linked to original sources
PubMed1977

Invasion of the duodenum by carcinoma of the stomach.

It has frequently been stated that extension to the duodenum occurs commonly in patients with gastric lymphoma but almost never in those with carcinoma of the stomach. We found radiographically detectable invasion of the duodenum in six of 111 consecutive patients (5%) with gastric carcinoma. The duodenum was involved microscopically in 18%. Radiographic abnormalities in the duodenum in 11 patients with proven transpyloric spread of tumor varied from irregularity of the base of the bulb narrowing and distortion extending well into the second portion of the duodenum. On the basis of these data and the reported frequency of transpyloric extension in gastric lymphoma, carcinoma appears to be the more likely diagnosis in a patient with duodenal involvement by an antral tumor.

Adenocarcinoma↗
PubMed1976

Early radiographic manifestations of carcinoma of the esophagus.

The survival of patients with esophageal carcinoma is greatest if treatment is begun when the tumor is small and confined to the esophagus. To better define the early radiographic manifestations of this disease, we analyzed the clinical and pathological information and the radiographs from 9 patients with esophageal carcinomas 3.5 cm or less in diameter. All tumors involved one wall of the esophagus and most appeared as plaques or flat sessile polyps, occasionally with central ulceration. Air-contrast views of the distended esophagus demonstrated the tumors to best advantage and should facilitate early detection.

Adult↗
PubMed1976

Radiographic evaluation of complications after jejunoileal bypass surgery.

A retrospective analysis of 89 patients who underwent jejunoileal bypass surgery for morbid obesity disclosed 33 complications that were detected radiographically. Intestinal obstruction (10.1% of patients), cholecystitis (5.6%), renal stones (4.5%), peptic ulcer (3.4%), megacolon (6.7%), and elongation of the small intestine with hypertrophy of the mucosal folds of the jejunum (6.7%) were diagnosed solely by radiographic means.

Adolescent↗
PubMed1976

Initial accuracy of esophagograms in detection of small esophageal carcinoma.

Esophagograms of 35 patients were interpreted without knowledge of clinical history by four diagnostic radiologists. Six esophagograms were of normal esophagi, 16 were of various benign disorders, and 13 were examples of small (less than 3.5 cm) esophageal carcinomas. Overall diagnostic accuracy averaged 58%. Small esophageal carcinomas were initially diagnosed accurately in 73% of cases. Of the 27% false negative diagnoses, 6% were interpreted as normal and 21% as benign abnormalities. Esophageal lesions in the form of ulceration surrounded by mass were most often diagnosed correctly as carcinoma. The most common error was interpretation of esophagitis, stricture, and ulcerated benign lesions as carcinoma. Esophagography was found to be a good screening procedure for detection of esophageal disease but not for accurate diagnosis of small carcinomas.

Aged↗
PubMed1975

Tetrachlorodibenzodioxin: an accidental poisoning episode in horse arenas.

Tetrachlorodibenzodioxin was identified as the apparent cause of an outbreak of poisoning in humans, horses, and other animals. Exposure was related to the spraying of contaminated waste oil on riding arenas for dust control. The contamination resulted from improper disposal of a toxic industrial waste. The pathologic effects and chemical identification of tetrachlorodibenzodioxin are described.

Aged↗
PubMed1975

Arteriographic demonstration of collateral arterial supply to the liver after hepatic artery ligation.

Eight patients were studied arteriographically after hepatic artery ligation (done to control bleeding in 6). Sources of arterial flow to the liver after ligation were (a) replaced or accessory hepatic artery; (b) interlobar collaterals in the liver; (c) right inferior phrenic artery; (d) through the gastroduodenal artery from arterial branches in the pancreas, duodenum, and omentum; (e) fine collateral branches of the gastroduodenal artery as they pass into the porta hepatis; and (f) recanalization of the ligated hepatic artery. Collateral vessels, seen as early as four hours after ligation, increase in size and number during the following six months.

Adult↗
PubMed1973

Tularemia.

Explore the source record for details and available documents.

Animals↗
PubMedDate not supplied

AIDS-related cholangiopancreatographic changes.

The cholangiographic and pancreatographic appearances of the acquired immunodeficiency syndrome (AIDS) associated cholangitis were evaluated in 26 patients. Twenty-four patients were diagnosed by retrograde cholangiography or endoscopic cholangiopancreatography (ERC or ERCP). One patient was diagnosed by T-tube cholangiography and another patient by transhepatic cholangiography. The radiographic findings ranged from intrahepatic ductal abnormalities with or without involvement of the extrahepatic biliary tree (eight patients) to irregularities and strictures involving the ampulla of Vater or the intrapancreatic portion of the common bile duct (CBD) with proximal dilatation (18 patients). Significant strictures involving the juxta-ampullary pancreatic duct were identified in six of 12 patients. Twenty-one of the 26 patients had associated infections which included: Cryptosporidium (CS), Mycobacterium avium intracellulare (MAI), cytomegalovirus (CMV), Microsporidium (MSP), and Isospora (ISP). Three patients were operated upon for acute acalculous cholecystitis. In each instance, organisms were identified in both the bile duct and the inflamed gallbladder.

AIDS-Related Opportunistic Infections↗
PubMedDate not supplied

In vivo measurement of hepatic iodine concentration using fluorescent excitation analysis.

Hepatic iodine concentration was measured in the live dog by external use of fluorescent excitation analysis. The number of characteristic photons produced by interaction of exciting radiation from an americium-241 source with iodine within the tissue is proportional to the tissue iodine concentrations. A correction is made for absorption of radiation by the abdominal wall and other tissues lying between the volume of liver being assayed and the detector collimator. The technique is applicable to the in vivo measurement of iodine concentrations from 0.5 to 40 mg/g. Accuracy of the technique is approximately +/- 10%, which is within the range of variation in iodine concentration at various sites within the liver. Radiation dose is low, and radiolabeled tracer compounds need not be used.

Animals↗
PubMedDate not supplied

Combined cholangiography and cholecystography using sodium iopanoate.

Cholangiography and cholecystography were performed in fasted dogs and human subjects using sodium iopanoate given intraduodenally in doses of 10 and 20 mg/kg. The same studies were performed after intraduodenal administration of fat or after intravenous administration of cholecystokinin (CCK) in dogs and after a fatty meal, to stimulate endogenous release of CCK, in human subjects. In both the animals and human subjects, peak blood iodine concentrations were reached by 30 minutes after iopanoate administration. At a dose of 10 mg/kg, radiographic visualization of both bile ducts and gallbladder was inconsistent. At 20 mg/kg (one-half the clinical dose for standard oral cholecystography,) the common bile duct was visualized within 60 minutes and the gallbladder within 90 minutes. Gallbladder density increased over the next 6 hours. Prior administration of fat or CCK led to earlier and denser gallbladder opacification. The common bile ducts opacified with the use of iopanoate were small in caliber, averaging only 3 mm. This probably reflects the fact that, unlike iodipamide, iopanoate has little or no choleretic effect. Therefore, because it would not increase the volume of bile in the duct, iopanoate would not increase duct size.

Adult↗