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Biomedical subjects

R E Matthews

Publications and source records attributed to R E Matthews.

At least 19 recordsLinked to original sources
PubMed1985

Viral taxonomy.

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Animals↗
PubMed1981

Intravenous reserpine for treatment of reflex sympathetic dystrophy.

The efficacy of reserpine in relieving the pain of reflex sympathetic dystrophy was tested in 25 patients--21 with upper extremity and four with lower extremity involvement. Injection of the drug relieved the acute signs and symptoms in the upper extremity in 12 of 17 patients. Four patients with quiescent reflex sympathetic dystrophy of upper extremities had prophylactic injection at the time of reconstructive surgery; they had no flare of symptoms. Relief was obtained in the four cases of lower extremity dystrophy. Our patients had no significant side effects. The drug is confined to the extremity by a pneumatic tourniquet as used for intravenous regional anesthesia. After the extremity is exsanguinated and the cuff is inflated, 1 mg of reserpine diluted to 50 ml with normal saline is injected intravenously into the upper extremity. In the lower extremity, 2 mg of reserpine diluted to 100 ml is injected. The tourniquet is removed after 15 minutes. The procedure is safe and can be done in an office setting.

Anesthesia, Conduction↗
PubMed1975

A classification of virus groups based on the size of the particle in relation to genome size.

For 59 different viruses, when the amount of nucleic acid in the particle is related either to the dry weight of the particle or to the particle volume, two classes of virus groups emerge--those with enveloped or those with geometrical particles. The enveloped viruses have particles with the following properties: (i) about 40 X 10-6 daltons of anhydrous weight per 10-6 daltons of nucleic acid; (ii) a particle volume of about 2 X 10-5 nm3 per 10-6 daltons of nucleic acid; (iii) a limiting lipoprotein membrane. These properties are qualitatively and quantitatively close to those of prokaryotic cells. The geometric viruses have particles with roughly one-tenth the anhydrous mass per unit of nucleic acid and one twenty-fifth the particle volume per unit of nucleic acid. They do not possess a limiting lipoprotein membrane.

Classification↗