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Biomedical subjects

R E Page

Publications and source records attributed to R E Page.

At least 19 recordsLinked to original sources
PubMed1995

Linkage map of the honey bee, Apis mellifera, based on RAPD markers.

A linkage map was constructed for the honey bee based on the segregation of 365 random amplified polymorphic DNA (RAPD) markers in haploid male progeny of a single female bee. The X locus for sex determination and genes for black body color and malate dehydrogenase were mapped to separate linkage groups. RAPD markers were very efficient for mapping, with an average of about 2.8 loci mapped for each 10-nucleotide primer that was used in polymerase chain reactions. The mean interval size between markers on the map was 9.1 cM. The map covered 3110 cM of linked markers on 26 linkage groups. We estimate the total genome size to be approximately 3450 cM. The size of the map indicated a very high recombination rate for the honey bee. The relationship of physical to genetic distance was estimated at 52 kb/cM, suggesting that map-based cloning of genes will be feasible for this species.

Animals↗
PubMed1989

Flexor tendon repair in zone 2 followed by controlled active mobilisation.

Over a two-year-period, 34 adult patients who had suffered zone two flexor tendon injuries to 38 fingers (70 tendons) were managed post-operatively by a regime of early active mobilisation. The results of this technique, assessed by the Strickland criteria after a mean follow-up period of 10.2 months, compared favourably with other more cumbersome methods.

Adolescent↗
PubMed1988

Carcinoma cuniculatum of the hand.

Carcinoma (epithelioma) cuniculatum is an uncommon variety of squamous cell carcinoma formerly considered to be limited to the foot. It has recently been reported in other parts of the body. We report a case in the hand and describe its management.

Carcinoma, Squamous Cell↗
PubMed1984

Immediate excision and skin graft of a friction burn in a replanted thumb with a note on its usefulness and indications.

A case is presented in which an area of friction burn was excised from the dorsum of a replanted thumb and the wound closed with a split-skin graft. In our experience successful revascularisation of similar injuries has often been followed by progressive venous failure. It is suggested that this technique, by decompressing the tissues, may prevent stagnation and propagation of thrombus, protect the interpositional graft and avoid subsequent venous failure with loss of the replanted digit.

Adult↗
PubMed1983

Microcirculation in hypertrophic burn scars.

Using the technique of capillary microscopy the microcirculation of post burn hypertrophic scars and grafts, at varying stages of maturity, have been documented. Sympathetic innervation of larger vessels beneath and within the scarred tissues could be found only in fully-matured scars, suggesting a link between the processes of scar reinnervation and maturation.

Adrenergic Fibers↗
PubMed1983

Management of the frostbitten hand.

Twenty cases of moderate and severe frostbite of the hands were analysed to establish trends in surgical treatment. Excision of large blisters and early mobilization in flamazine bags were found to be beneficial. In those patients whose initial skin changes did not extend to the base of the fingers only minor amputations were necessary. The small amounts of necrotic tissue did not interfere with hand movement and operation was therefore delayed until six or seven weeks, so that maximal digital length could be preserved. In contrast, those patients whose initial skin changes involved the whole length of the fingers or extended on to the hands, more proximal amputations were necessary and these amputations were performed at three to four weeks in order to remove the larger amounts of necrotic tissue and facilitate early mobilisation.

Adolescent↗
PubMed1982

Normal lip function in adults.

A superficial review of the literature revealed numerous types of surgical corrections for lip defects, but an in-depth search turned up little information on lip dimensions and functions. In the absence of a range of normal lip values, assessment of postoperative results is limited to the subjective impression of surgeon and patient. Using simple measuring techniques, some of the surgically important aspects of lip anatomy and function have been recorded, analyzed statistically, and presented as a range of normal values to facilitate objective comparison with abnormal and postoperative lip states.

Adult↗
PubMed1981

Hypospadias revisited.

A careful histological study of chordee tissue obtained in 30 consecutive cases of hypospadias has shown the presence of a considerable amount of smooth muscle. Preputial skin contains some elastic tissue. This feature may well provide significant advantages in the use of tubed preputial skin for urethral repair.

Humans↗
PubMed1980

The evolution of multiple mating behavior by honey bee queens (Apis mellifera L.).

A model is presented showing that natural selection operating at the individual level can adequately explain the evolution of multiple mating behavior by honey bee queens. Group selection need not be invoked. The fitness of a given female genotype is a function of the number of sex alleles in the population, the number of matings by an individual female and the specific parameters that determine the relationship of brood viability to individual fitness. Even though the exact relationship is not known, it is almost certainly not linear. A nonlinear relationship between worker brood viability and fitness and a significant genetic load associated with the sex-determination system in honey bees are the essential components of this model.

Animals↗
PubMed1979

Surgical correction of the hand in epidermolysis bullosa dystrophica.

Epidermolysis bullosa dystrophica (polydysplastic type) is a rare congenital skin anomaly which, in the hands, because they are exposed to repeated trauma, results in a severe "mitten"-like deformity. Functional benefit was obtained in three patients by separation of the digits and application of split-thickness grafts. Wolfe grafts or "split-off" (epidermis) grafts. Arthrodesis of the interphalangeal joints and filleting of the little finger to provide a flap which could be turned in to the palm, resulted in an improvement in hand function.

Adolescent↗