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R E Ritts

Publications and source records attributed to R E Ritts.

76 records · Page 5Linked to original sources
PubMedDate not supplied

Induction of peripheral blood lymphocyte transformation by autologous synovial fluid lymphocytes and synovial fluid.

Synovial fluid lymphocytes and synovial fluid from most patients with rheumatoid arthritis induced blastogenesis of autologous peripheral blood lymphocytes. In vitro transfer of the mitogenic activity of the synovial fluid to peripheral blood lymphocytes was not accomplished, but diminished response of the peripheral blood lymphocytes to phytohemagglutinin stimulation after incubation in synovial fluid was demonstrated. These findings suggest that a similar blastogenic response in vivo may induce the lymphoid hyperplasia regularly observed in rheumatoid arthritis.

Arthritis, Reactive↗
PubMedDate not supplied

Correlation of preoperative immunologic test results with recurrence in patients with head and neck cancer.

Numbers and percentages of T and B cells in peripheral blood; blastogenic responses to PHA, Con A, and PWM; and serum levels of albumin, total protein, and IgA were assessed in patients with stages I to III operable squamous cell carcinoma of the upper aerodigestive passageways in the head and neck. The patients were categorized into two groups: those who remained tumor free and those in whom cancer recurred. It was found that pretreatment PHA- and Con A-induced blastogenesis was often depressed in patients in whom clinically apparent recurrences developed regardless of stage or nodal involvement. This point is consistent with the idea that cellular immune function (blastogenesis) can identify, within the clinical staging system (TN), subpopulations of patients who are less likely to survive after conventional therapy.

B-Lymphocytes↗