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Biomedical subjects

R E Scholtens

Publications and source records attributed to R E Scholtens.

3 recordsLinked to original sources

Treatment of recurrent squamous cell carcinoma of the hand in immunosuppressed patients.

Since 1981, 14 patients with kidney transplants have been treated for recurrent squamous cell carcinoma of the skin of the dorsum of the hand by total skin resection. Frozen sections of the base of the tumor sites were carried out and the denuded area was resurfaced with split-skin grafts harvested from non-sun-exposed areas on the buttock and upper thigh. During follow-up examinations, no recurrence was seen in the grafted areas. The appearance was good and hand function was satisfactory.

Adult↗

Resurfacing the back of the hand as treatment and prevention of multiple skin cancers in kidney transplant recipients.

BACKGROUND: Skin cancer is a serious problem in renal transplant recipients. In some patients numerous skin cancers develop on the back of the hand. Instead of repeated excisions, a more radical procedure may be necessary. For these patients a new surgical therapy is available: resurfacing the back of the hand. OBJECTIVE: Our purpose was to clinically evaluate this new procedure. METHODS: Eleven kidney transplant recipients who underwent resurfacing of the back of the hand were analyzed in a retrospective follow-up study. With this surgical procedure the skin of the entire dorsum of the hand is excised and split-skin grafts harvested from thigh and buttock skin are then placed. Information was gathered from the medical records and questionnaires, and by physical examination. RESULTS: The mean follow-up time was 4.7 years. No recurrences of skin cancer were observed in the transplanted skin. The cosmetic appearance was acceptable, and there were few side effects. CONCLUSION: Resurfacing the back of the hand can be a successful treatment for carefully selected patients with multiple skin cancers on the back of the hand and can be used prophylactically in patients with severely actinically damaged skin.

Adult↗

Subcutaneous phycomycosis.

Subcutaneous phycomycosis, a uncommon fungal infection of the human skin, is discussed and a representative case is described. Subcutaneous phycomycosis is a chronic, progressive fungal infection of the deeper layers of the human skin that causes localized, mobile, firm and non-tender swellings. The causative organism is the Basidiobolus haptosporus, a fungus commonly found in rotting vegetation in the soil.

Child, Preschool↗