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Biomedical subjects

R E Sneider

Publications and source records attributed to R E Sneider.

4 recordsLinked to original sources

Diagnosis and treatment of pulmonary disorders of patients with the acquired immunodeficiency syndrome (AIDS).

It is apparent that the lung is frequently involved by a number of opportunistic pathogens and neoplasms in AIDS patients. What is even more disconcerting is the fact that often several infections or infection and neoplasm can coexist [236]. At this time, although effective therapy is at hand for most of the disorders mentioned, the patient's underlying immunodeficiency prevents any long-term survival and also usually leads to relapse when treatment is discontinued. Perhaps the use of newer antiviral compounds such as azidothymidine [237] or immunomodulating agents will help to reconstitute the waning immunocompetence and allow more durable responses in these currently fatal complications.

Acquired Immunodeficiency Syndrome↗

Bradycardia induced by negative acceleration.

Four volunteers were subjected to negative acceleration in a human centrifuge for the purpose of testing a standard lap belt. Three subjects developed a sinus bradycardia. The fourth developed a sinus arrest with a junctional rhythm at -2 G. With return to +1 G, the sinus mechanism recovered with a prolonged P-R interval. Within 2 h, the P-R interval returned to normal. Negative acceleration maneuvers, well within the capabilities of high-performance aircraft, can effect marked changes in the cardiac rhythm. This phenomenon appears to be vagally induced and is remarkably well tolerated.

Acceleration↗