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Biomedical subjects

R Eichen

Publications and source records attributed to R Eichen.

At least 19 recordsLinked to original sources
PubMed1978

[Acute haemorrhage from ulcers of the stomach and duodenum; rate of transfusion and complications (author's transl)].

It has been shown in 35 patients with severe acute gastrointestinal haemorrhage that there is a limit regarding the amount of transfused blood needed for substitution. Whereas patients over 65 years had a 100% mortality rate after more than 10 units., the limit in younger patient was 15 units. The time of the beginning of surgical therapy is decisive for the chance of survival. After 4 transfusions in few hours the surgical intervention should be started. Under these conditions even older patients have a better chance of survival. The number of transfusions given and the time is directly proportional to the rate of complications.

Adult↗
PubMed1978

[Duodenal cancer. A clinical-pathological study].

Seven primary carcinomas of the duodenum were observed from 1973 to 1976 at the University Hospital Hamburg; four in females and three in males with an age between 32 and 69 years of age. The interval between the first symptoms (epigastric pain, jaundice, pruritus, diarrhea, and loss of weight) and surgical therapy (duodeno-pancreatectomy) averaged four months. All carcinomas were resected radically from the macroscopic (intraoperative) aspect as well as from the histological findings. Local tumour recurrences which proved fatal occurred in five patients within nine to twenty-one months. One patient died of peritonitis and another of pancreatitis. The diagnostic mode has been changed since the introduction of endoscopy and retrograde cholangio-pancreaticography (ERCP). The consistent inclusion of the duodenum in routine gastroscopy leads to the hope that more carcinomas of the duodenum can be detected early.

Adult↗
PubMed1977

[Cancer risk of the stomach resected for ulcer. The role of duodenogastric reflux (author's transl)].

The purpose of this study was to find whether the reflux of bile and pancreatic juices following stomach resection (duodenogastric reflux) enhances the incidence of carcinomas near the gastroenteric anastomosis. 72 male Wistar rats were subjected to stomach resection. The gastroenteric anastomosis (GE) was performed either as short loop anastomosis (Billroth II; n = 39), thus providing a continuous duodenogastric reflux, or as Y-shaped GE (according to Roux; n = 33). By the latter technique, bile and pancreatic juices are derived quantitatively into the jejunum without coming into contact with the remaining part of the stomach. During a period of 33 weeks, operated rats as well as intact animals were given the carcinogen N-methyl-N'-nitro-N-nitrosoguanidine (NG; 120 mg/l) in the drinking water. At autopsy, 33 to 36 weeks after daily oral administration of NG, most of the tumours were found in operated rats undergoing continuous reflux (Billroth II group). In contrast to these findings, the incidence or carcinomas was significantly lower in animals without reflex (Roux group or intact control rats).-The results of our experiments demonstrate that, in rats, the duodenogastric reflux contributes substantially to the development of carcinomas of the resected stomach.

Adenocarcinoma↗
PubMed1977

[Islet cell tumors. Diagnostic and operative aspects (author's transl)].

Islet cell tumors have been described the past 25 years in frequent series. Multiple symptoms lead often to prolongation of disease and misinterpretation of diagnosis. Because of its rarity most authors report only few cases. We had the chance to observe 24 patients of which four had carcinoma within 12 years. Symptoms, clinic, different surgical procedures are described. Clinical difference seems to exists between benigne and malignant islet cell tumors.

Adenoma, Islet Cell↗
PubMed1977

[Radiation protection measurements at the intensive care unit and in the operating room].

For chest X-ray in the ward and for intraoperative cholangiography the registered doses were low. A limitation of the exposures or the operations was not necessary. For osteosynthesis operations the doses for the patient and the staff could be kept low by preparing the operation adequately, by using modern image-intensifer units with grid and automatic regulation in fluoroscopy, and with discipline in using fluoroscopy. During one week a surgeon could do eight osteosynthesis operations without reaching legally imposed dose limit. The control area could be restricted to a space around the patient with a radius of two meters.

Germany, West↗
PubMed1977

[Gastroenterostomy, indications--complications--reparation (author's transl)].

After presenting the indications of the gastroenterostomy in accordance with current valid pronciples, the early and late postoperative disturbances and their corrections are described. The main immediate complications is the gastric paralysis of the stomach and later the peptic jejunal ulcer. Conservative therapy as well as possible, surgical treatment, especially the degastroenterostomy with and without resection are mentioned.

Aged↗
PubMed1977

[The thoracic stomach. Etiology--diagnosis--therapy].

Congenital, acquired, and traumatic defects of the diaphragm are reported. Special consideration is given to positional changes of the stomach due to the above lesions. Clinical examples are used to point out the diagnostics and surgical possibilities of reparation.

Abnormalities, Multiple↗
PubMed1976

[A special closure system of the gastrointestinal tract of the rat (author's transl)].

As a result of animal experiments, morpho-histologic and surgical findings, the presence of a new closure system of the gastrointestinal tract is described. The mode of action is different from that of all the known muscle sphincters. It is found in the ascending colon of the rat and consists of a specially arranged and adjustable mucosal folds with aunique vascularisation. A functional unit which comosed of a pair of folds and a vascular plexus constitute the valvular mechanism. We, therefore, consider appropriate to call it the Angioplical Closure System. Surgical reversion of even a very small portion of the system causes a lethal ileus.

Ampulla of Vater↗