Biomedical subjects

R F Brem

Publications and source records attributed to R F Brem.

3 recordsLinked to original sources

PubMed1992

Template-guided breast US.

The authors modified a standard breast compression plate to allow ultrasound (US) scanning to be performed in the longitudinal and transverse directions with the breast positioned craniocaudally or laterally in a mammographic unit. The technique allows quick mammographic-US correlation of lesions, characterization of lesions as cystic, solid, or indeterminate, and the ability (with coordinates marked on the plate) to proceed directly with aspiration of sonographically indeterminate lesions.

Breast Neoplasms↗

PubMed1991

Nonpalpable prostate cancer: detection with MR imaging.

The pathologic specimens and magnetic resonance (MR) images of 53 patients with clinically palpable prostate cancer confined to one lobe were studied to evaluate the ability of MR imaging to depict clinically nonpalpable prostate cancer. All patients had undergone imaging with a 1.5-T imager with T1- and T2-weighted sequences in both axial and sagittal planes before undergoing radical retropubic prostatectomy. At pathologic examination, only the palpable tumor was present in 30 of the 53 patients (57%), and 33 unsuspected tumors were present in an area distinct from the palpable tumor in 23 of the patients (43%). MR imaging successfully depicted 51 palpable tumors for a sensitivity of 96% and 19 of the 33 unsuspected tumors for a sensitivity of 58%. The sensitivity of MR imaging in the detection of nonpalpable, posteriorly located tumors was greater than for those located anteriorly (85% vs 15%). MR imaging was false-positive for nonpalpable tumor in 17 of 30 patients for a specificity of 43%. On the basis of these data, MR imaging has greater sensitivity in the depiction of posteriorly located cancer and is limited by a high false-positive rate in the depiction of nonpalpable tumors.

False Positive Reactions↗

PubMedDate not supplied

MR detection of breast implant rupture.

Breast implant rupture can be difficult to diagnosis. Various modalities including direct clinical palpation, ultrasound, CT, and mammography have been used to evaluate for the presence of prosthesis rupture. We report a case in which the presence of breast implant rupture was determined using MR with characterization of the inflammatory reaction in the soft tissues around the implant. The absence of ionizing radiation with MR makes it especially well suited for evaluating implant rupture in younger patients in whom breast irradiation should be minimized.

Breast↗