Biomedical subjects

R F Jiménez

Publications and source records attributed to R F Jiménez.

3 recordsLinked to original sources

PubMed2001

Time-frequency analysis of arterial pressure oscillations in anesthetized dogs: effects of standardized hemorrhages.

The purpose of this preliminary study was to investigate the advantages of the time-frequency analysis through the Continuous Wavelet Transform (CWT) compared to classical Fourier analysis using the Fast Fourier Transform (FFT) in arterial pressure signals from anesthetized mongrel dogs before and during standardized hemorrhages. Systemic arterial pressure pulsations were recorded using catheter-tip manometers. CWT and FFT were applied to arterial pressure pulsations to obtain module coefficients of this transformation and its associated contours during the evolution of progressive hemorrhages, in amounts of 15, 34, and 66% of the estimated total blood volume. This mathematical analysis enabled us to identify the evolution of the frequency components of aortic valve functions, heart dynamics, respiratory influences, and vasomotor activities. Furthermore, we isolated the modulating signal of amplitude modulation phenomenon present in the arterial pressure records, as described in previous papers, being the heart rate carrier frequency. The CWT is a very sensitive and reliable procedure to analyze (time-frequency) the oscillatory phenomena in two dimensions, and to provide more information than the FFT. This new analytical procedure may provide new insights in the study of shock pathophysiology.

Animals↗

PubMed1997

Continuous wavelet transform of aortic pressure oscillations in anesthetized dogs: effects of 45 degrees tilting.

The time-frequency analysis of signals by means of continuous wavelet transform (CWT) was applied to blood pressure oscillations recorded from the aorta of anesthetized dogs. This method yielded two and three-dimensional representations of either the module or phase in function of time, in contrast with the fast Fourier transform (FFT) which gives the spectrum in the frequency domain. From the CWT of arterial pressure oscillations we obtained visual information on aortic valves closure, heart rate, respiratory rate and smooth muscle contractions in arterial and arteriolar walls (very low frequency component). The objective of this study was to analyze the frequency-time behavior in two and three-dimensional cardiovascular changes during 45 degrees head-up and head-down tilts, compared with zero degree supine position. In eight pentobarbitone anesthetized dogs, the postural changes were repeated for more than ten times in each one. Heart rate variability was derived by applying a new mathematical procedure. We utilized the pronounced changes of heart rate during each respiratory cycle (inspiratory tachycardia and expiratory bradycardia) to establish a correlation with the arterial pressure fluctuations during normal and tilting conditions. Significant differences in heart rate were observed between the 45 degrees head-up and head-down tilts, compared with the supine position. The results show that anesthetized dogs might constitute an appropriate model where to study orthostatic hypotension and microgravity blood shifts.

Anesthesia↗

PubMed1973

[Congenital hypothyroidism].

A case of primary congenital hipothyroidism, with acentuated symptoms of myxdema together with great psychic and physical deficiency, is referred to. The out standing clinical findings were an increase in pubic hair and sings to right ventricular hypertrophy, whose pathogeny is commented. The clinical evolution after three years of treatment, and the necessity of begining treatment as early as possible so as to obtain greater efficiency in the recuperation of psychic deficency, is also referred to.

Child, Preschool↗