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Biomedical subjects

R F Mabon

Publications and source records attributed to R F Mabon.

3 recordsLinked to original sources

Fluid dynamics in cerebral angiography.

Flow field characteristics are described so that the physician may have a better understanding of the mechanical effects of rapid intravascular injection of a highly ionized hypertonic solution. Theoretical and experimental results which illustrate the fluid dynamics involved are presented. This knowledge may be helpful in diminishing the overall complication rate in cerebral angiography and in outlining the carotid arterial complex, which is frequently the site of dense atheromatous plaque deposition.

Arteries

Measurements of disordered flows distal to subtotal vascular stenoses in the thoracic aortas of dogs.

Instantaneous blood velocity measurements employing a constant temperature hot film anemometer were obtained in the region distal to externally enforced, subtotal vascular stenoses in the descending thoracic aortas of anesthetized dogs. Our objectives were to determine alterations in velocity waveforms and energy spectra as the degree of stenosis was increased. We paid particular attention to distinguishing features of the flow which were characteristic of turbulence. Our results indicate that, for the vessels studied, disturbances in the velocity waveforms occur for very minor localized constrictions. The energy spectra follow certain similarity parameters within a restricted region of the distal velocity field. For severe stenoses relatively high levels of energy exist in frequency ranges which previously have been found to produce poststenotic dilation. The measurements suggest that velocity waveforms and energy spectra provide a very early clue to the existence of localized occlusive vascular disease in larger vessels and that, within a limited region distal to a stenosis, the degree of constriction may be estimated by similarity analysis of the energy spectra.

Animals