Biomedical subjects
Publications and source records attributed to R F Rosenberg.
Three cases of vincristine-induced megacolon are described with radiographic correlation. Vincristine is a widely used chemotherapeutic agent with neuropathic side effects causing colonic dilatation and constipation. The radiologist should be aware of this entity to prevent unnecessary procedures and, possibly, surgery.
Four cases of giant colonic diverticula are presented with emphasis on plain film recognition employing the "balloon sign", a persistent, rounded lucency which is consistently seen on any abdominal scout film or survey. The importance of this finding is even greater in the absence of gastrointestinal complaints in view of the complication of torsion and perforation.
Six patients with Crohn's disease had colonic intraluminal multilobulated masses detected on barium enema. Four had Crohn's colitis and two ileocolitis. The mean duration of disease was four and eight tenths years. Three patients underwent surgery and three had colonoscopy with multiple biopsies and cytology. Pseudopolypoid inflammatory tissue was found in each case. One patient died after a prolonged postoperative course due to sepsis and abscess formation. No surgery was performed in three patients and follow-up colonoscopic examinations at four and a half years revealed no change in these findings. The presence of an intraluminal colonic mass in Crohn's colitis may mimic a neoplasm. If surveillance with x-ray, endoscopic biopsies and cytology reveals pseudopolypoid inflammatory tissue then surgery is not mandatory. Pseudopolypoid inflammatory tissue has never been associated with carcinoma.
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A case of an extremely rare, benign ovarian lesion occurring in young women is presented and its pathology discussed. Radiographically it simulated a large calcified fibroid. The diagnosis should be considered in a young woman with menstrual irregularity and pelvic mass where fibroma and thecoma are unlikely.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.