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Biomedical subjects

R Fötzsch

Publications and source records attributed to R Fötzsch.

At least 19 recordsLinked to original sources

[Ptosis as the leading symptom of Kearns-Sayre syndrome. A case report for differential diagnosis of external ophthalmoplegia].

Progressive external ophthalmoplegia has generally been considered a brainstem syndrome, but new investigative techniques have identified a variety of etiologies. We report a 17-year-old girl in whom Kearns-Sayre syndrome presented as unilateral ptosis with progression to bilateral ptosis, and discuss the clinical, biochemical, electrophysiological, histopathological and computerized tomographical findings.

Adolescent↗

[Behavior of visual evoked potentials (pattern reversal VECP) in smokers].

Twenty six clinically healthy smokers were studied with transient pattern visual-evoked potentials. In comparison with a sample of "normal" subjects we found a difference of some parameters (P less than 0.05): the P2-latency and the interocular difference of latency on average were 6-7 ms respectively 2 ms larger. Thirteen subjects have had a prolonged P2-latency (P less than 0.05) and/or a difference in interocular latencies larger than 5 ms. These findings may suggest on subclinical disturbances of visual system and indicators of an special sensitivity of that person. The findings are possibly related to tobacco-alcohol amblyopia.

Adult↗

[Significant manifestations and diagnostic difficulties in chronic secondary hypoparathyroidism].

A man became ill with insufficiency of parathyroid glands 10 years after strumectomy. Numerous brain organic changes were apparent (severe epileptic seizures, tonic seizures of the brain stem, pathological EEG, PEG and liquor symptoms, papilledema, marked mental disturbances ranging in severity up to episodic psychoses), but even at the climax of the illness there were no definite signs of tetanic seizures, so that the basic illness remained unidentified for several months. Chronic secondary hypoparathyroidism was not definitely identified until ectodermal changes appeared, the characteristic changes of the lens contributing greatly to final diagnosis.

Adult↗

[Psychopathology and neuro-ophthalmology in meningioma of the olfactory groove].

In 14 patients with a surgically nad histopathologically verified meningioma of the olfactory nerve groove (OGM) (12 women, 2 men), clinical findings and diagnosis were analysed, especially with respect to neuropathology and psychopathology. The apodictic theorem that an OGM leads to a Foster-Kennedy syndrome as well as to a psychopathological orbital brain syndrome cannot be maintained. The Foster-Kennedy syndrome does not occur in a characteristically high incidence, and psychopathologically an orbital brain syndrome can only be diagnosed in case of an anterior location of the OGM. The more the OGM shows starting point or growth development to or from the anterior chiasmal angle, the more is resembles that psychopathological syndrome that we have found and described for the meningioma of the Tuberculus sellae.

Brain Neoplasms↗

[Neuro-ophthalmology and psychopathology of meningiomas of the tuberculum sellae (syndrome of the anterior chiasma angle)].

Seventeen cases of meningiomas of the Tuberculum sellae (the anterior chiasma angle) are analysed according to neuro-ophthalmological and psychopathological aspects. Although they also develop in the so-called suprasellar space, they are not characterised by heteronymous bitemporal hemianopsia, but it is in most cases the primary, bilateral optic atrophy that is predominant. Six of 17 cases showed--as the case reported by E. Lange in 1963 ("hysterical" amaurosis)--psychopathological initial and leading symptoms and with these a psychopathological complex which is called a medio-basal hypothalamic-limbic brain-localised psychosyndrome.

Blindness↗

[Retinal vein periphlebitis - frequency, occurrence and diagnostic significance].

Among 15,000 neuroophthalmological patients examined in the years 1963 to 1977, 51 showed periphlebitic changes of the retinal veins. 46 of these patients were known to suffer from multiple sclerosis (MS). From his results that changes of the fundus of the eye are associated with a high degree of probability (about 90 per cent) with multiple sclerosis. In the same period of time, 422 patients were found to suffer from MS. From this one can calculate the relative frequency of periphlebitic changes of the retinal veins in MS cases to be about 10.9 per cent. Apart from their diagnostic importance, the findings are also interesting because they may indicate the significance of periphlebitic changes in the etiopathogenesis of MS.

Adult↗

[Ophthalmophlegic polyneuritis. A clinical contribution to Fisher's syndrome].

This paper describes 6 patients with the syndrome of ophthalmoplegic polyneuritis fairly identical to that described by Fisher. The most striking symptom of the ophthalmoplegic polyneuritis is the acute ophthalmoplegia, usually total and bilateral, often with sparing of the pupillary reflexes and of the levater palpebrae. The disturbances may simulate a paralysis of gaze or a internuclear palsy. Following features may announce this illness: mild harmless infectious disease, sensory deficits, generalized hyporeflexia or areflexia, albuminocytologic dissociation. There is without a specific treatment a complete recovery within months. Often it is impossible to clarify the etiology.

Aged↗

[Symptomatology and pathogenesis of Fisher's syndrome].

The symptomatology of Fisher's syndrome is described with reference to observations made on six own cases as well as to fifty cases described in the literature, and it is shown that, first, ataxia is not an obligatory symptom and that, second, symptoms are an expression, not of a lesion of the brain stem, but of an affection of the peripheral neuron.

Aged↗