Biomedical subjects
Publications and source records attributed to R Fabi.
From a review of the literature on this subject it emerges that around 6-7% of women are injured during the course of pregnancy. Road accidents, falls and domestic accidents are the most frequent events: it is therefore important to provide pregnant women with information to prevent such events which may endanger both maternal and fetal health.
In order to identify the role played by heterochromatic polymorphisms in miscarriage, an analysis was carried out on 257 couples, 137 of them with two or more abortions and 120 serving as a control. All couples were taken from two Italian populations: 77 cases and 70 controls came from an exogamic population whilst 60 cases and 50 controls came from an almost endogamic one. Out of the 137 cases, six couples in the exogamic and five in the endogamic groups were excluded because at least one partner had balanced chromosomal aberrations. Four controls from the exogamic group were also excluded for the same reason. The remaining 126 cases were analysed to detect the presence of chromosomal heteromorphism in one or both partners. The results suggested that chromosomal heteromorphism does not induce miscarriage. In fact, only one heteromorphism, inv(9)(p11q12), seems to be marginally related to recurrent abortion and only in the exogamic population. In addition no differences were found in the distribution of chromosomal heteromorphism in the couples analysed in relation to the number of abortions, i.e. two or more than two.
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Pregnancy is a stage of maturation crisis which, like other moments of crisis in a woman's life (adolescence and menopause), is characterised by phases of regression, the weakness of mental defences and transformation of the image of self. When there are conflicts with femininity, the experience of pregnancy may be complicated and unease may be expressed in somatic symptoms such as nausea and vomit, and may even lead to the onset of pathologies such as hypertension, miscarriage and pre-term labour. This has led to the term "psychological" risk pregnancy being used over the past 20 years.