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Biomedical subjects

R Ferro

Publications and source records attributed to R Ferro.

At least 19 recordsLinked to original sources
PubMed1991

Quantitation of melphalan in plasma of patients by reversed-phase high-performance liquid chromatography with electrochemical detection.

An analytical procedure for the separation and determination of melphalan in human plasma was carried out. A simple high-performance liquid chromatographic method with electrochemical detection was developed taking advantage of the high sensitivity of the electrode redox reaction. The sample pretreatment consisted of a direct extraction of the interferents rather than of melphalan, owing to the difficulty of extraction of the drug, and was very simple, rapid and reproducible.

Administration, Oral↗
PubMed1991

[The evaluation of and comments on a regional experience of dental prophylaxis. The relations between school, local health screening units and the Veneto region].

The paper analyses the opinion and proposals which emerged from a series of meetings held between the local health units, school representatives and the Department of Health of the Veneto Regional Government in the context of a regional plan for oral and dental hygiene aimed at kindergarten and primary school children. In addition to the traditional sensitivity of schools with regard to health-related problems, in the future in would be advantageous to involve families directly at the level of pediatric outpatient clinics (in order to create an adequate clinical back-up), thus removing dental care from a strictly educational context.

Child↗
PubMed1990

[The quadrilateral of prevention. Comments and reflections on the operative methodology in dental prophylaxis in Italy].

The authors have evaluated their experience in the field of dental prevention accumulated over the course of the past few years. It is apparent that there is considerable interest in projects aimed at restricted target groups, in this case children between 6-7 years old. Attention is also focused on synergies deriving from the collaboration between doctors (dentists and non-dentists), teachers, parents and public officials.

Child↗
PubMed1990

[Empathy and prevention: from the child's viewpoint. Comments on a school diary developed from dental prophylaxis messages].

The paper presents, explains and comments on the theoretical, practical and applied aspects of a collaborative enterprise between Health Services and a primary school in the context of a dental hygiene and preventive project organised by the USSL no. 19 in Mediobrenta. The enterprise in question concerned the experimental writing, by the children themselves, of a school diary, based on messages regarding dental health and hygiene formulated by the Odontostomatological Service in line with learning processes and communication models used during infancy. The experiment formed part of the general active approach of modern psychological pedagogy, and proved particularly efficacious in introducing medical concepts to an infantile population which would otherwise have met with much greater resistance.

Child↗
PubMed1989

Excretion of aminoglycosides in a rat kidney model.

Dactimicin is a new aminoglycoside antibiotic with an interesting low nephrotoxicity in animal experimental models. In order to establish if a correlation exists between the nephrotoxic effect and renal pharmacokinetic behaviour of aminoglycosides, tobramycin, sisomicin and dactimicin were studied in a model of isolated and perfused rat kidney. Concentrations in venous and urinary effluent during a continuous perfusion of a constant concentration of drugs were evaluated. The influence of active transport was studied comparing excretion data obtained with perfusion buffer with or without glucose. In the present experimental model the renal excretions of the aminoglycosides tested are quite similar and cannot account for the different nephrotoxicity observed in animals.

Aminoglycosides↗
PubMed1986

Another Italian family with mandibuloacral dysplasia: why does it seem more frequent in Italy?

We describe three patients (one female and two males in a sibship of 11) with mandibuloacral dysplasia. Only eight families have been reported previously, and of these, four were of Italian origin. The phenotypic spectrum of the condition is delineated and its variability is stressed. The observation of three affected members of both sexes with normal parents supports the hypothesis of autosomal recessive inheritance. The reasons for the high frequency of the condition in Italy are discussed; a local selective advantage for heterozygotes and founder effect might be involved.

Abnormalities, Multiple↗