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Biomedical subjects

R Flynn

Publications and source records attributed to R Flynn.

13 recordsLinked to original sources
PubMed1988

Plasma concentrations of bupivacaine during extradural anaesthesia for caesarean section. The effect of adrenaline.

The clinical effects and plasma levels associated with the use of 0.5% bupivacaine with and without the addition of 1:200,000 adrenaline (5 micrograms/ml) were studied in 30 patients who underwent extradural anaesthesia for elective Caesarean section. The addition of adrenaline to bupivacaine prolongs analgesia, reduces the degree of hypotension and delays its onset. Plasma bupivacaine levels were consistently lower when adrenaline was added, but this difference was significant only at 10 minutes after the initial dose. Prolonging the interval between increments seems to be a more reliable way to reduce plasma concentration than the addition of the catecholamine.

Anesthesia, Epidural↗
PubMed1983

Acute chemical meningitis after metrizamide-lumbar myelography.

Severe acute meningitis developed after the use of metrizamide for lumbar myelography; cerebrospinal fluid findings included a white blood cell count of 2300, mostly polymorphonuclear cells, glucose level of 8 mg% and protein level of 253%. This apparent chemical meningitis could not be distinguished, either clinically or by cerebrospinal fluid examination, from acute bacterial meningitis. This case emphasizes that severe acute meningeal reactions, while very rare, can occur after the use of metrizamide for myelography. Such patients must be evaluated promptly to rule out bacterial meningitis and should be followed carefully for possible later sequelae.

Acute Disease↗
PubMed1980

Bacterial meningitis after myelography.

Two cases opf bacterial meningitis due to streptococci occurred following Pantopaque myelography. These are, to our knowledge, the first reports of Streptococcus mitus and group G streptococcus causing meningitis in this situation. These 2 cases emphasize the importance of considering the possibility of bacterial meningitis following myelography and the difficulty in differentiating it on clinical grounds from the more common aseptic meningitis that occurs after myelography. They also emphasize the importance of maintaining strict sterile technique during myelography.

Adolescent↗
PubMed1979

Fluorescein angiography in retrolental fibroplasia: experience from 1969-1977.

Acute proliferative retrolental fibroplasia (RLF) has been studied in premature infants employing a Zeiss fundus camera and fluorescein angiography. A total of 164 angiograms have been performed on 122 infants. At the present time, angiography is reserved for studying infants with peculiar or puzzling fundus pictures. A dose of 0.1-0.4 cc of 10% sodium fluoresceinate is employed, depending on the age and the weight of the baby. Fluorescein clearly outlines the major arteriovenous shunt in the retina, which is the hallmark of acute RLF. The shunt fills with fluorescein and leaks it profusely. On regression, a fine brush border of capillaries is seen in the region where the shunt previously had been located. Study of the population susceptible to RLF reveals it to be the smallest sickest babies in the premature nursery.

Female↗