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R Franchi

Publications and source records attributed to R Franchi.

At least 55 records · Page 3Linked to original sources

Angioscintiphotography with 99mTc in 310 cases of space-occupying kidney lesions.

Angioscintiphotography with 99mTc has been performed in 310 cases of space-occupying kidney lesions with the purpose of establishing the diagnostic value of the kidney perfusion. In the presence of a neoplasm, a more or less marked blood flow in the lesion generally appears as a hot area. This pattern is not observed in poor vascularized carcinomas or in Wilms' tumors. The percentage of poorly vascularized tumors is moderate and does not affect the value of the method. Cystic lesions appear usually to be cold. Large cysts exhibit no uptake; on the contrary, the degree of vascularization in the small cysts is more difficult to evaluate, as the normally supplied surrounding parenchyma overlaps the cold area caused by the cyst. In the evaluation of the angioscintiphotographic picture, we must take into account the concomitant hepatic or splenic vascularization, which may cause some doubts of interpretation because of projection interferences. The renal angioscintiphotography has an important rule in specifying the nature of a space-occupying kidney lesion and may be regarded as a useful screening test.

Adenocarcinoma↗

[Contribution of clinical, biohumoral, morphological and instrumental parameters to the diagnosis of some chronic liver diseases].

A comparative study concerning the diagnostic importance of clinical, humoral, morphological and instrumental parameters had been carried out on 105 patients affected by chronic liver disease (51 cases with liver cirrhosis, 15 with metastatic tumors, 10 with liver steatosis and 29 with chronic hepatitis). The final diagnosis of the patients used for the comparison was formulated considering the greatest numbers of data. The results of this study can be drawn as follows: --clinical and laboratory data show satisfactory diagnostic value principally in patients suffering from liver cirrhosis (90 per ceny) and metastatic tumors (93 per cent); --peritoneoscopy appears to be generally the most useful procedure with the most significance value above all in cirrhotic patients; --morphological examination in biopsy specimen results of the greatest importance in patients affected by chronic hepatitis and hepatosteatosis while rather high has been the percentage of false negatives in secondary tumors of the liver (40 per cent) and cirrhosis (68 per cent); --scintiphotoscanning is generally less useful as a diagnostic tool than peritoneoscopy a part of the cases of metastatic tumors. In such a condition the diagnostic power of both the procedures results to be identical; --it may be concluded that an integrating diagnostic information generally results to be the most precise and maximally capable of reducing the number of false negatives. In individual cases, of course, the less important procedure shows to have the maximum of diagnostic capacity.

Biopsy, Needle↗

Regional left ventricular ejection fraction with single crystal gammacamera and gated equilibrium technique: repeatability and inter-observer variability.

Regional left ventricular ejection fraction calculated by means of gated blood pool scintigraphy was compared with that obtained from contrast ventriculography in a group of 20 patients, submitted to both procedures within a month. To evaluate repeatability both at rest and during stress, a second scintigraphic study was carried out after three weeks, with no change in drug regimen. Inter-observer variability was assessed in a randomly selected subgroup of 16 patients, in whom a computation was repeated by a second operator. Comparison of scintigraphic results showed a satisfactory agreement, and measurement agreement for global left ventricular ejection fraction was very good. As regards interobserver variability, each of the three myocardial segments examined (septal, lateral and infero-apical) showed good agreement. As regards repeatability, global left ventricular ejection fraction, proved readily reproducible both for rest and stress studies, with relatively small differences in observed values. Regional ejection fraction, on the other hand, had a high variability, especially during stress. It is suggested that for regional ejection fraction evaluation, reproducibility studies should be performed in order to better correlate result changes to clinical outcome after medical or surgical therapy.

Aged↗