Biomedical subjects

R Frank-Ricci

Publications and source records attributed to R Frank-Ricci.

7 recordsLinked to original sources

PubMed1988

Stereotactic biopsy and treatment of brain stem lesions: combined study of 33 cases (Bologna-Marseille).

Intraaxial brain stem tumours are rarely treated by open surgical technique. In Bologna and Marseille, 23 and 10 stereotactic biopsies respectively were performed in patients with brain stem mass lesions. The mortality due to biopsy was 3% (1 pat.); while the morbidity was temporary in 6 cases (18%) and permanent in one patient (3%). The approach to the brain stem was via a frontal burr hole. 7 times, after biopsy and histological diagnosis, radioisotope implant of the neoplasm was performed with 125I (iodine). From the histological diagnoses of the lesions the following was found: only 40% of the young patients had highly malignant tumours; 83% of the adults had neoplasms (not all of the malignant type), while 17% of the verified lesions were non-neoplastic. Since a diagnosis of the lesion nature is impossible with current neuroradiological means, the authors noting a variety of masses found in their experience, emphasize the importance of stereotactic biopsy, as a scarcely invasive method to give a precise diagnosis and a possible treatment.

Adolescent↗

PubMed1987

Stereotaxis and abnormal movements.

A series is presented of 106 patients with extrapyramidal syndromes treated by stereotaxy. The importance of preoperative screening to assure favorable results is stressed. Surgical contraindications are elderly patients with dementia and akinesia. Axial dystonia and spasmodic torticollis respond poorly to stereotaxy; and bilateral interventions should be avoided.

Humans↗

PubMed1987

Smear biopsy for on-the-spot diagnosis in stereotactic surgery of CNS tumors. Experience of 101 cases.

We report the correlation between cytological and histological diagnoses in 101 stereotactic biopsies performed on space-occupying lesions of the CNS. Diagnostic accuracy was 89%, in line with the rates reported by other workers.

Biopsy↗

PubMed1987

Late considerations in the treatment of low-grade malignancy cerebral tumors with iodine-125 brachytherapy.

The authors report their series of 45 patients harboring inoperable, low-grade cerebral neoplasms, treated in the past 6 years with 125I stereotactic brachytherapy. The majority of these tumors were grade I and II astrocytomas and oligodendrogliomas (82.2%). A 2.6- to 6-year follow-up shows good results in 65.6% with reduction or disappearance of the lesions on CT images and good social reentry. Nine patients (23.7%) died prior to follow-up. Young patients (less than 40 years) responded well to interstitial radiotherapy, while patients over 40 with the same histological findings of low-grade tumors responded poorly to this type of treatment. Diffuse infiltrating cortico-subcortical tumors, optochiasmatic gliomas, hypothalamic and lower brainstem neoplasms do not respond satisfactorily to 125I radioisotope implantations.

Brachytherapy↗

PubMed1987

Stereotaxy and thalamic masses. Survey of 44 cases.

Thalamic masses are generally considered inoperable; little is known of the precise nature of these lesions. Stereotactic biopsy was performed in 44 patients, with no mortality and low morbidity (only 1 case of transitory hemiparesis). The stereotactic biopsy (minimum 5 specimens taken along the major axis of the lesion) showed that the majority of the young patients (less than 40 years) had low-grade glial neoplasms (grade I-II astrocytomas or oligodendrogliomas), while in older patients highly malignant tumors prevailed. Beside the neoplasms in the children and adults, we found granulomas, abscesses, infarcts, hemorrhages and glioses. Present neuroradiological methods cannot establish a final correct diagnosis in thalamic lesions, so stereotactic biopsy is recommended. A follow-up of 1-6 years is presented for 7 patients who underwent stereotactic 125I brachytherapy.

Adolescent↗

PubMed1985

Treatment of low malignancy brain neoplasms by means of stereotactic interstitial radiotherapy.

The authors report their results of 37 patients with low malignancy brain tumors seated in deep or highly functional areas not amenable to traditional surgery, nor to conventional radiochemotherapy. In the past 5 years these patients were treated by means of stereotactic interstitial radiotherapy. The isotope employed in all cases was 125I. Stereotactic radioisotope implants were always preceded by multiple stereotactic biopsies affording precise histological diagnoses. A 6-month to 5-year follow-up shows a survival rate of 72.6% (29 patients), and of these patients, 80.9% (26 out of 29) had complete social reentry.

Brachytherapy↗

PubMedDate not supplied

Stereotactic radioisotope implantations in the treatment of inoperable low malignancy neoplasms.

The authors report their experience of 53 patients with low grade malignancy cerebral neoplasms treated by means of stereotactic 125-I permanent interstitial radiotherapy. The method has been employed from 1981 to date. The authors confirm the validity of the technique in this brief report, and stress the greater efficacy of this treatment in young patients (less than 40 y/o) than in adults.

Adult↗