Biomedical subjects

R Fuenzalida

Publications and source records attributed to R Fuenzalida.

7 recordsLinked to original sources

PubMed1995

[Active labour management in primiparas. Prospective study].

The objective of our study was prospectively compare the effect in the rate of cesarean section of active labor management and of traditional labor management in primiparas with physiological term pregnancy. From september 1, 1993 to may 31, 1994, 145 primiparas with physiological term pregnancy were randomly assigned to one group of active labor management (study group, n = 75) and to one group of traditional labor management (control group, n = 70). Cesarean section rate was 9.3% in the study group and 20% in the control group (p < 0.05). There was no increase in fetal morbidity or mortality. Active labor management can reduce cesarean section rate in primiparas with physiological term pregnancy.

Adult↗

PubMed1995

[Development of products for the elderly population: vitamin enriched pudding].

An instant dessert powder, pudding type was developed to be consumed at lunch or dinner time. The dessert was designed to be prepared in skim milk and meets the nutritional needs of elderly people. The dessert contains modified starch, carragenine, vegetal fat, sacharose. Each serving has been enriched with 30% of the daily vitamin requirement advised for adults over 51 years old. The optimized process was carried out according to the Karlsruhe test. Each serving consists of 22g powder prepared in proportion of 18% in skim milk. The optimized dessert powder was controlled by means of physical, chemical and microbiological analyses. The sensory quality was determined in the ready to eat product and the acceptability level was measured in a group of people selected according to the characteristics of the target population. The dessert powder contains 1.1% protein, 5.2% fats, 89.76% carbohidrates, and provides 409 Kcal/100g. Both the sensory and microbiological quality were good and the level of acceptance reached 98%.

Aged↗

PubMed1994

[Development and optimization of an isotonic sports drink].

Within a research program on food products for athletes starting from natural apple concentrate, the design, manufacture and control of isotonic beverages, was undertaken. The dilution conditions for the apple concentrate were established studying several salts combinations which will supply those electrolytes that are eliminated through sweat and have to be replenished. They are sodium, potassium, chloride, magnesium and calcium in concentrations such as to supply an osmotic pressure similar to that observed in blood. The addition of a premix of vitamins (B1, B2, B6, B12, C, E, folic acid, niacin, pantothenic acid and biotin) in several levels of the Recommended Daily Allowance (RDA) (100, 75, 62.5, 60 and 30% of the RDA) was assayed. The obtained formula tasted salty and medicine-like, therefore the vitamin content had to be reduced, supplying 30% of the RDA in a premix constituted by those vitamins which are the most important for physical activity (B1, B2, B6 and C). The quality of the formula was optimized considering variables such as flavor, color and maltodextrin levels by using methods of sensory evaluation. In the elaborated beverage controls such as pH, acidity, total solids (degree Bx), relative density and soluble solids/acidity ratio complying with the corresponding standards, were carried out. In addition, chemical composition, caloric value, microbiological and sensory quality, were controlled. The fruit juice was packed in a 250 ml self-supporting"Doy-Pack"-like bag. Both, microbiological and sensory quality were good, and the caloric value was 101.18 Kcal/250ml. Shelf life studies at two different temperature conditions 15-25 degrees C and 3-5 degrees C, were carried out. The limiting factor was flavor which defined a shelf life of at least 3 months, stored at refrigeration temperature (3-5 degrees C). The formulated beverage supply the electrolyte concentrations which allows to be characterized as isotonic beverage, recommended for athletes.

Beverages↗

PubMed1980

Effect of glomerulopressin and mannitol in acute renal failure in rats.

Glomerulopressin is a hormone that increases glomerular filtration rate (GFR) in toads, rats, and dogs. In this study, the effect of glomerulopressin was assayed in two models of acute prerenal failure, by haemorrhage and by partial occlusion of the aortic artery. In animals with 30 min of anuria both mannitol and glomerulopressin increased GFR and urinary flow, but if the rats were anuric for 120 min, only glomerulopressin was effective in restoring GFR and urinary flow. Glomerulopressin also restored GFR and urinary flow in animals that had remained anuric for 24 hours.

Acute Kidney Injury↗

PubMed1979

Effect of glucagon and glomerulopressin on the renal function of the dog.

Glucagon was infused through the porta or through the left renal artery in dogs. Another group of dogs were infused with glomerulopressin through the left renal artery. It was observed that glucagon when infused through the portal vein enhanced the glomerulopressin production and the glomerular filtration rate (GFR). When glucagon was infused intrarenally it did not alter GRF but it had a direct tubular action decreasing sodium reabsorption in the proximal tubule. Glomerulopressin infused intrarenally increased GRF and potassium excretion. The results suggest that the increase in GFR was due to increase in glomerulopressin activity. There are three reasons for this statement: a) GRF increased when glomerulopressin activity was high, but not when there was a low activity, 5) intrarenally infused glomerulopressin produced a very significant change in the GFR of the infused kidney, while the GRF of the contralateral kidney remained unchanged and c) intrarenally administered glucagon had no effect on GFR.

Animals↗

PubMed1978

Effect of glucagon on glomerulopressin production in diabetic dogs.

Glucagon (21.5 +/- 0.23 ng/min/kg) was infused through the portal vein of normal or pancreatectomized dogs. It was observed that a dose of glucagon that produces no significant change in the glycemia of normal dogs has a very small activity in the production of glomerulopressin and does not alter glomerular filtration rate (GRF). In pancreatectomized dogs this same dose of glucagon also does not alter glycemia but it induces a large increase in the production of glomerulopressin and GFR. Our results suggest that in pancreatectomized dogs glomerulopressin production is more sensitive to glucagon infusion than in normal dogs.

Animals↗

PubMed1977

Increased glomerular filtration rate and glomerulopressin activity in diabetic dogs.

Studies of the chemical characteristics of glomerulopressin were carried out, and the results suggest that glomerulopressin is a glucuronic acid conjugate. Glomerulopressin activity, glucuronide concentration and glomerular filtration rate (GFR), plasma volume (PV), extracellular volume (ECV) and estimated hepatic plasma flow (EHPF), were measured in normal dogs, infused with saline or glucose and in pancreatectomized dogs infused with saline. Glomerulopressin activity, glucuronide concentration and GFR were also measured in pancreatectomized dogs infused with insulin (150 muU/min/kg) through the portal or femoral vein. The glomerulopressin activity, glucuronide concentration and GFR in glucose-infused normal dogs were similar to those observed in saline-infused animals, while they were greatly increased in pancreatectomized dogs. There was no difference between these three groups in PV, ECV, or EHPF. The infusion of insulin through the portal vein of pancreatectomized dogs reduced glomerulopressin, glucuronides and GFR to the values observed in normal dogs, while the infusion on insulin through the femoral vein did not decrease these levels. The increased glomerulopressin produced by pancreatectomy seems to be due to the lack of insulin reaching the liver. The results suggest that pancreatectomy induced an increase of glomerulopressin activity and that this humoral factor increases GFR.

Animals↗