Nonenzymatic glycation of platelet proteins in diabetic patients.
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Biomedical subjects
Publications and source records attributed to R Fullerton.
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Serum levels of total cholesterol, triglyceride, high-density lipoprotein-cholesterol (HDL-C) and apoprotein-HDL (apo-HDL) have been measured in adults of Busselton, Western Australia (males, n = 1600; females, n = 1968) and the distribution of values by age and sex are reported. The data confirm previously reported trends with age for cholesterol and reveal strikingly different ranges and trends with age for triglyceride between males and females, mean values in males increasing more rapidly with age and showing greater variation and more marked positive skew. Mean HDL-C values show little change with age in males, and a slight rise with age in females, up to the 7th decade, and then a fall. Apo-HDL levels show very similar distributions to HDL-C in each sex.
In a mass health examination conducted in the Shires of Cunderdin and Tammin, 83% of subjects on the electoral rolls attended for screening of cardiovascular risk factors including fasting blood lipid measurements. Fasting serum triglyceride levels are presented. Other factors measured showed quite close similarities to those in the Busselton 1972 Health Survey. On conventional criteria of percentage of desirable weight, fasting serum cholesterol level and fasting serum triglyceride level, a very large proportion of the survey population was found to be eligible for preventive dietary advice--for example, 50% of males and females aged 40 to 59 years. The effective education and after-care of subjects found to be at risk requires further development of resources.
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