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Biomedical subjects

R Fusco

Publications and source records attributed to R Fusco.

32 records · Page 2Linked to original sources
PubMed1986

Inheritance of Brown's syndrome.

Two families are described with members affected by Brown's syndrome. Another case of Brown's syndrome is described in a dizygotic twin. The authors suggest a hypothesis for the influence of heredity in Brown's syndrome.

Child↗
PubMed1983

Morphological and physiological changes of the eye in patients with congenital heart disease undergoing extracorporeal circulation.

We studied 76 patients with congenital heart disease, whose ages ranged from 2 to 39 years. The following investigations were carried out pre-operatively and post-operatively in all patients: visual acuity, cycloplegic refraction, orthoptic examination, examination of the fundus. Where collaboration was sufficient the following were also studied: kinetic and static perimetry, adaptation perimetry, colour vision, electroretinography. There were no differences before and after operation of visual acuity, adaptation perimetry, refraction, electroretinography or of the fundus. Post-operative changes were only found in 4 of the 65 patients in whom perimetry was performed. By comparison, an identical study of patients with acquired heart disease showed the percentage of functional ocular changes to be higher in this group.

Adolescent↗
PubMed1982

Ocular manifestations in thalassemia minor.

The authors report the results of a study on 96 subjects affected with thalassemia minor. The study was made at the Center for the Study of Microcythemia of the OORR in Naples. Of extreme scientific interest is the finding of ocular involvement in 33.3% of the cases. Therefore, after formulating a pathogenetic hypothesis, the authors plan more involved studies and research on these patients.

Adult↗
PubMedDate not supplied

Topically applied levobunolol does not cause changes in the corneal endothelium.

The corneal endothelium was examined in ten patients suffering from ocular hypertension before, during and after four months of topical levobunolol treatment. The untreated fellow eye served as a control. The number of endothelial cells, determined with a McIntyre eyepiece and an Eisner's contact lens, was not affected by levobunolol therapy. In addition, the morphology of the cell did not appear to be affected by the drug.

Administration, Topical↗
PubMedDate not supplied

Trabeculectomy and extracapsular cataract extraction with posterior chamber lens implantation: a long term study.

Extracapsular cataract extraction with posterior chamber lens implantation and trabeculectomy was performed on 15 cataractous eyes in 15 patients: 5 were affected with chronic closed angle glaucoma and 10 with primary open angle glaucoma. This procedure offers the intraocular pressure control expected after trabeculectomy and, at the same time, gives the patients all visual benefits that cataract extraction with intraocular lens implantation warrants, without the introduction of new complications.

Aged↗
PubMedDate not supplied

Long-term effects of befunolol on the corneal endothelium and the consensual ophthalmotonic reaction.

In a double-blind study, 30 patients with ocular hypertension were randomly assigned to receive one drop of 0.5% befunolol or placebo (the drug vehicle) in each eye twice daily for 120 days. The befunolol used contained no preservatives. Before and after treatment the number and shape of the endothelial cells of the five corneal sectors were evaluated. After 120 days of twice-daily application of befunolol or placebo, no changes in the shape or density of the corneal cells were found in any patient. No differences in the patients receiving befunolol or placebo were noted. The consensual ophthalmotonic reaction was studied in 15 of the patients before and after befunolol administration. A significant decrease in intraocular pressure was noted at 30 minutes and at 1, 2, 3, 4, 5, and 6 hours after befunolol. Intraocular pressure also decreased significantly at 1 to 4 hours after placebo, and then returned to pretreatment levels at 6 hours.

Adrenergic beta-Antagonists↗