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Biomedical subjects

R G Akopian

Publications and source records attributed to R G Akopian.

At least 19 recordsLinked to original sources

[Percussional auscultation of frontal sinuses].

Percussional auscultation of the frontal sinuses is used for diagnosis of frontal sinusitides. Phonendoscope placed by the sinus walls auscultates sounds forming as a result of comparative percussion of the anterior sinus walls. Three main percussional tones are singled out. This method was employed for diagnosis in 48 patients with frontal sinusitis. The technique is easy to perform, safe and precise (90%). The trend in frontal sinusitides development can be followed up.

Adult↗

[The use of tranexamic acid as an anesthetic component in ENT surgeries in patients with high surgical-anesthetic risk and in hemorrhagic shock intensive therapy].

Experimental and clinical trials have shown that anesthesia and intensive therapy of shock incorporating tranexamic acid enhance analgesia, hyporeflexia, thus ensuring stable, adequate anesthesia which is safe under reduced doses of standard anesthesiological modalities. Application of tranexamic acid provided more favourable course of postanesthesiological and postoperative periods, decreased the number of complications and lethal outcomes compared to standard anesthesia.

Adult↗

[Trephanopuncture of the frontal sinuses: the evolution of the method].

Historical evolution of frontal sinus trepanopuncture with description of its benefits and shortcomings is presented. The perfection of the method lies in introduction of technological innovations raising safety of the procedure and provision of the approach sufficient for modern therapeutic and diagnostic techniques.

Frontal Sinus↗

[Use of nonopiate agents for anesthesia in ENT patients at high surgical-anesthesiological risk].

Optimal methods of endotracheal anesthesia using non-opiate drugs of four classes (clofelin, transamine, contrykal, ketanes) have been fundamentally grounded developed and tried in extensive and traumatic operations for ENT malignant and vascular tumors as well as inflammation in patients of high anesthesiological operative risk. The drugs were used in 174 patients including 13 children. 87.9% of the patients had concomitant diseases: blood hypertension, coronary heart disease, chronic nonspecific pulmonary diseases, bronchial asthma, asthmatic bronchitis, diabetes mellitus, anemia. Adequate stable anesthesia was achieved in reduced dosage of conventional anesthesiological agents.

Adolescent↗

[Benign tumors of the laryngopharynx].

Benign tumours of the laryngopharynx are mainly vascular tumours. Thirty two persons with the given pathology were under observation. The main clinical symptoms of the disease are the appearance of blood in the sputum, dysphonia, dyspnea of different degree. The method of choice is radical surgical intervention including tracheotomy, laryngotomy, transverse and lateral pharyngotomy, ligation of the external carotid artery.

Adult↗

[Experience in the use of extracorporeal correction of the immune system in the treatment of patients with LOR cancer].

Correction of the immune status is one of the burning problems of current otorhinolaryngology. Recent developments in immunology allow interference at the cellular level. However, otorhinolaryngological practice is still based on oral, parenteral or local use of ineffective drugs. This paper presents early results of the application of extracorporeal cytapheresis combined with the modulator treatment of lymphocytes for the surgical therapy of 25 patient with ENT malignant neoformations of different stage and localization. Leukocytapheresis, i. e. separation of leukocytes, was performed by means of an Aminco (USA) or FK-3,5 (USSR) cell separator and the separated cells were treated with diuciphone. This method yielded good results as suggested by immunological, immunochemical, biophysical, and cytological measurements of blood. The method seems promising for ENT-cancer therapy.

Cytapheresis↗