[Determination of the leukocyte poisoning index in blood preparations with a dry stain zone].
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Biomedical subjects
Publications and source records attributed to R G Ambartsumian.
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The work presents results of investigations of the biochemical composition of lymph and the degree of its toxic properties in the process of its detoxication by lymphosorption and ultrafiltration. The degree of toxic properties of the central lymph when purified by the above methods was established to be considerably lower while the energetic value of the lymph subject to reinfusion remains sufficiently high.
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The activity of elastase, elastase inhibitor and isozymes of lactate dehydrogenase (LDH) was studied in 11 dogs with experimental pancreatitis and 5 control dogs. All dogs with experimental pancreatitis died 6--14 hours after the induction of pancreatitis. Morbid anatomy studies proved severe pancreonecrosis. The results obtained show that after the induction of pancreatitis the elastase blood activity increased 3-fold as compared with the initial level, and remained unchanged up to the animals' death. At the same time the activity of elastase inhibitor fell, correlating with the rise in elastase activity. Also there was a disproportion between LDH 1 and LDH 2 which became more conspicuous to the 3d hour, and an increase in LDH 5 by the end of the experiment. A conclusion is made that dysfunction of the liver may be one of the causes of the decreased inhibitory activity of elastase in pancreonecrosis.
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