[Method of analysis of the hydroelectrolitic composition of skin and skeletal muscle, experimental study in rats].
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Biomedical subjects
Publications and source records attributed to R G Bevilacqua.
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A young female patient had a recurrence of severe spherocytic anemia there years after having been submitted to splenectomy. The presence of two accessory spleens with a size of 3.5 cm and 4.0 cm, was demonstrated by technetium scanning and ultrasound images. Surgical removal of these noduli resulted again in prompt recovery. The development of the spleen beings in the fifth week of intrauterine life at the dorsal mesogastrium. The lack of fusion of splenic lobuli is responsible for the occurrence of accessory spleens. A surgeon performing splenectomy for the treatment of hemolytic anemia should always search for possible existences of accessory spleens.
The authors report on a study conducted to analyze the professional situation of physicians residing in the State of São Paulo, Brazil, five years after completion of a medical residency program. At least 50% of the professionals were interviewed in each specialty. A heavy work load was observed in physicians working both in the metropolitan area of the State capital and in other regions of the State. Male doctors had a higher income than female ones. The latter, however, had a higher proportion working in a single specialty, although 16.8% did not practice in the specialty in which they were trained. The most frequent working environment was a hospital, followed by an ambulatory facility and a private office. The metropolitan area physicians exceeded the remaining in teaching activities and public hospital appointments. They had also a higher tendency to work in a different specialty. This study offers significant information with respect to professional decisions as well as regarding the creation or expansion of residency programs.
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The authors review the cases of traumatic rectal injuries admitted to the Emergency Service of the "Hospital das Clínicas", University of São Paulo Medical School, during the period of July 1981 to July 1988. Forty-five patients (62.5%) had their injuries due to gunshot, 14 (19.4%) due to foreign bodies on the rectum, 10 (13.8%) due to blunt trauma and 3 (4.1%) due to stab wounds. The intraperitoneal rectum was injured in 32 patients (44.4%) and extraperitoneal portion of the rectum in 40 patients (55.5%). On the intraperitoneal injuries the management adopted were simple suture (14 patients), associated with a colostomy (17 patients) and in one patient the Hartmann procedure was adopted. On the extraperitoneal wounds the management adopted were rectal repair (when feasible), colostomy, distal washout and drainage. The complications rate was 27.8%, and from them, the majority (70%) were related to infectious nature. Seven patients died (9.7%), four of them as a consequence of sepsis. The morbidity and mortality of the rectal injuries were closed related to infectious complications as a consequence of late diagnosis. For this reason, the authors consider that all efforts should be employed to establish the prompt diagnosis.
Body composition parameters were studied in different nutritional conditions in Wistar rats with experimental cancer. Results were submitted to statistical analysis. Under a hyperlipidic diet, fat increased in control rats and decreased in animals with tumor; sodium increase and potassium decrease was verified in rats with tumor. The NA/K ratio increased in both groups and the N/K ratio increased in rats with tumor under standard diet, but decreased in rats with tumor under hyperlipidic diet. Fat decreased in the animals with tumor under an aproteic diet, but sodium increased. Potassium increased in undernourished animals of both groups. The Na/K ratio increased in rats with tumor. A comparison was made according to two different standards: "fresh body weight" and "fat-free body mass". The parameters analysed showed no significant differences in body composition.
Two cases of perforated duodenal diverticulum, treated at the surgical Emergency Service of the Hospital das Clínicas of the University of São Paulo Medical School are reported. Although duodenal diverticula are frequent their perforation in is a rare and dougerous complication. Diagnosis and surgical treatment are discussed. We believe that excision, primary suture with an omental patch and drainage are procedures of choice for the treatment of this complication.
In Wistar rats bearing a Walker-256 carcinoma flank tumor, a standard skin wound was inflicted on the backs of the animals. Nitrogen intake and nitrogen balance measures were obtained. The standard wound did not promote tumor growth. Wound contraction in tumor-bearing animals was not different from that in tumor-free animals. Tumor-bearing rats had anorexia, lower nitrogen intake and a tendency to lower their nitrogen balance. These findings suggest that both cancer and wound healing are privileged metabolic events, having as a consequence sacrifice of the host.
The authors review the cases of complex pelviperineal injuries admitted to the Emergency Service of the Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo during the period 1983-1988. The management of these patients followed a protocol that consisted of: exhaustive lavage of the injury with extensive debridement, leaving the wound widely unsutured, matured loop colostomy, lavage of the distal colon, scheduled revisions at 48 to 72 hour intervals, intensive antibiotic treatment and early total parenteral nutrition. Thirty one patients were treated following these procedures, with a decrease in mortality due to sepsis from 50% to 16.1%.
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