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Biomedical subjects

R G Breeze

Publications and source records attributed to R G Breeze.

At least 73 records · Page 4Linked to original sources
PubMed1978

Monensin and the prevention of tryptophan-induced acute bovine pulmonary edema and emphysema.

3-Methylindole, a ruminal fermentation product of tryptophan, induces acute pulmonary edema and emphysema in cattle, and 3-methylindole is present in the ruminal fluid and blood of cows with a natually occurring form of this disease. Monensin, a polyether antibiotic and widely used feed additive for beef cattle, prevented tryptophan-induced acute bovine pulmonary edema and emphysema. Monensin acted by reducing the ruminal conversion of L-tryptophan to 3-methylindole both in vitro and in vivo. Lasalocid, also a polyether antibiotic, showed similar effects in vitro. These results provide a promising approach to prevention of this major respiratory disease of cattle.

Animals↗
PubMed1978

Myxoma of the equine respiratory tract.

Bronchial myxoma occurred in an aged Arab mare with longstanding respiratory disease wrongly attributed to chronic obstructive pulmonary disease. Blood gas and maximum intrathoracic pressure change measurements were not consistent with this latter diagnosis, and this was supported by aerosol antigen provocation tests. Radiography demonstrated a hilar mass in the thorax, and this proved to be a myxoma at necropsy.

Animals↗
PubMed1977

Thrombosis of the cranial vena cava in a cow.

Thrombosis of the cranial vena cava in a cow was followed by the formation of aneurysms in the pulmonary arteries. Embolism, pulmonary hypertension and the development of a collateral venous and lymphatic circulation are the suggested causes of these uncommon arterial lesions.

Aneurysm↗
PubMed1977

Arthrogryposis-palatoschisis and a 1/29 translocation in a Charolais herd.

The congenital condition of arthrogryposis palatoschisis was found in two closely related Charolais calves and has subsequently been found in a number of other related animals. It would appear from this and earlier reports that the condition is inherited, possibly as an autosomal recessive. A 1/29 Robertsonian translocation was also found in one of the calves and this was inherited from its dam. It is considered that the two conditions are not directly related.

Animals↗
PubMed1977

Effects of 3-methylindole in cattle.

1 Rapid intravenous injection of 3-methylindole (3-MI) was shown to induce an anaphylactoid-like reaction in calves. 2 This was suggested by the reduction in response to a repeat dose of 3-MI, by the reduction of effects in the presence of antagonists to the putative mediators of anaphylaxis in cattle and by the production of signs similar to those seen in experimentally induced bovine anaphylaxis. 3 The plasma half-life of 3-MI was short (14.4 min) and, since absorption of 3-MI from the rumen is known to be slow, the extent of formation of 3-MI from L-tryptophan in the rumen would have to be substantial if 3-MI is to be considered the causative agent of 'fog fever', an acute respiratory distress syndrome seen in cattle.

Animals↗
PubMed1976

Pulmonary arterial thrombo-embolism and pulmonary arterial mycotic aneurysms in cattle with vena caval thrombosis: a condition resembling the Hughes-Stovin syndrome.

Sixteen cattle affected by thrombosis of the posterior vena cava were examined post mortem and the various lesions are described. The thrombus was in the hepatic portion in 12 animals and in the intrathoracic part in four. Thrombi had formed as a result of phlebitis in 13 cases in which hepatic or post-diaphragamatic abscesses were present but the aetiology of the other three was not discovered. Embolism from the vena cava thrombus resulted in pulmonary lesions in every case: these included pulmonary arterial thrombo-embolism, pulmonary arteritis, pulmonary endarteritis, chronic suppurative pneumonia and the formation of multiple pulmonary abscesses. The pulmonary arterial lesions had given rise to mycotic aneurysms of that vessel and rupture of these was followed by massive haemoptysis or intrapulmonaary haemorrhage. Pulmonary arterial aneurysms are not common in man and are very rare in animals, except in association with vena cava thrombosis of cattle. However, the "Hughes-Stovin" syndrome of man has some features in common with the condition described in cattle and these are discussed. The different sequelae of posterior vena cava thrombosis and infective endocarditis of the right heart in cattle are also considered.

Aneurysm, Infected↗
PubMed1975

Acute respiratory distress in cattle.

The term "fog fever" was originally used identify a disease of adult cattle grazing lush pastures in the autumn. Unfortunately, the name has subsequently been applied to other respiratory disorders which occurred under different epidemiological circumstances, so that the name "fog fever" has lost much of its original specificity and become almost synonymous with "acute respiratory distress". The pulmonary lesions in 151 cattle, of all ages, with acute respiratory distress are described in this report. While most of the animals were referred as examples of "fog fever", in only 43 of the 151 cases were the clinical signs, epidemiology and post mortem findings consistent with that disease. Twelve other pulmonary disturbances were encountered in the other animals and the pathology of these conditions has bee described.

Animals↗