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Biomedical subjects

R G Michel

Publications and source records attributed to R G Michel.

13 recordsLinked to original sources

Tomographic diagnosis of palatal defects.

We present the results of a pilot study conducted to evaluate the effectiveness of palatal tomography in patients suspected of having palatal defects not detectable by other methods. Twelve patients were involved in the projects, ranging in age from 3 to 11 years. There were 8 boys and 4 girls. Each patient was evaluated with voice recordings, lateral cineradiographic x-rays, and palatal tomograms. Nine of the 12 patients were found by tomography to have palatal defects that had not been detected either by cineradiography or by clinical investigation, including physical examination of the palate. The results of this study are presented with clinical findings.

Child

Ceruminous gland adenocarcinoma: a light and electron microscopic study.

Tumors of ceruminous gland origin in the external auditory canal are rare in man. A case is described in which such a tumor presented as an invasive vascular temporal bone neoplasm, mimicking a glomus jugulare tumor. Light and electron microscopic study of this tumor confirmed a diagnosis of ceruminous gland adenocarcinoma. Tumors of ceruminous gland origin appear to have a distinctive clinical behavior by virtue of their unique anatomical location in the external auditory canal. Our experience with this case establishes another clinical picture characterizing the histologic type of ceruminoma designated as a ceruminous gland adenocarcinoma. We feel that the generic term "ceruminoma," with its implied histologic subgroups, is useful to the clinician when he encounters a tumor arising from the modified sweat glands of the external auditory canal.

Adenocarcinoma

Diagnosis of palatal defects by trispiral tomography: a pilot study.

A pilot study is presented in which 12 selected patients, ages 3-11 years, were evaluated for a palatal defect utilizing trispiral tomography. Each patient, because of speech and hearing abnormalities, was evaluated by a speech pathologist and an otolaryngolgist and voice recordings, audiometry, tympanometry and plain and cine radiographic X-rays were obtained. Those children with speech and hearing abnormalities in whom the question of a palatal defect was raised underwent trispiral palatal tomography. Nine of the 12 patients selected for tomography demonstrated a palatal defect that was not detected by other means. Trispiral tomography appears to be a useful tool in the diagnosis of suspected palatal defects in selected patients.

Child

Parasympathetic nerve section for control of sialorrhea.

Twenty mentally retarded patients with a considerable drooling problem underwent transtympanic sectioning of selected preganglionic parasympathetic nerve fibers to the major salivary glands. Following surgery, cessation of trouble-some sialorrhea occurred in 15 to 20 patients; but by six months postoperatively, only ten patients remained controlled. The best results obtained were in a subgroup of five patients who underwent bilateral Jacobson nerve and chorda tympani nerve section. In four of these patients, sialorrhea was controlled after a minimum follow-up of two years. Parasympathetic denervation of the major salivary glands via a transtympanic approach is offered as a primary modality of therapy in those mentally retarded patients judged to have considerable sialorrhea. Sacrifice of both chorda tympani nerves appears to enhance the surgical results.

Adolescent

Sjögren's syndrome and serous otitis media.

Extrasalivary lymphoid abnormalities in Sjögren's syndrome are well described. Patients have been found to have lymphoid infiltration of many organ systems. The nature of the lymphoid abnormalities constitutes a spectrum ranging from benign to malignant disease. A case of an elderly patient with long standing Sjögren's syndrome is presented because of the unusual manifestation of a benign lymphoid mass in the nasopharynx producing unilateral eustachian tube obstruction and serous otitis media. Serous otitis media associated with Sjögren's syndrome is recognized, but to our knowledge in previous cases an extrasalivary lymphoid abnormality has not been implicated as the underlying pathology.

Aged

Infectious mononucleosis, mastoiditis, and facial paralysis.

To our knowledge this is the first report of a patient with infectious mononucleosis associated with a mononuclear granulomatous mastoiditis and facial paralysis. Pathologic examination of tissue from this patient, removed at the time of radical mastoidectomy, provides a basis for further speculation about the relationship between facial paralysis and infectious mononucleosis.

Adolescent

Angioneurotic edema. A review of modern concepts.

We review the subject of angioneurotic edema with special emphasis on the more clearly defined entity of hereditary angioneurotic edema. The clinical presentations of the various forms of angioneurotic edema are discussed. Attention is directed toward the attempts that have been made to define this group of diseases in terms of their underlying biochemical mechanisms. A simplified schema of the serum complement system is presented. We conclude that only after we understand such biochemical interactions will we able to effect a more definitive form of therapy for the angioneurotic edemas.

Acute Disease

Exostosis of the mandibular coronoid process.

Abnormal enlargement of one or both mandibular coronoid processes may lead to a limited mandibular excursion. A case of unilateral coronoid process exostosis severely limiting mandibular function is described. A review of the literature pertinent to this uncommon abnormality is presented. The various entities of coronoid process osteochondroma, osteoma, exostosis, hypertrophy and developmental anomaly, all producing a similar picture of coronoid process enlargement are discussed. The proper use of the available radiographic techniques simplifies the diagnosis of these uncommon maladies, as long as a coronoid process abnormality is considered in the differential diagnosis of restricted mandibular movement.

Adult

Extracranial meningioma.

A patient is presented with findings of separate intracranial and extracranial meningiomas, each of a different histologic type. A calcified fibrous meningioma, with secondary psammomatous features, presented as a left neck mass associated with hoarseness, dysphagia, a unilateral facial weakness and hearing loss. A noncalcified asymptomatic intracranial syncytial meningioma was discovered in the left frontal lobe after computerized tomographic and angiographic study of the cranial contents. The origin of the extracranial meningioma producing multiple unilateralcranial nerve disturbances and serous otitis media is discussed. The noncontiguous tumors in this patients are felt to have separate origins, with the extracranial lesion most likely arising in the temporal bone.

Brain Neoplasms

Evaluation of sclera as a homograft in facial plastic and reconstructive surgery.

Augmentation of deficient soft tissue contours accounts for a large part of facial plastic and reconstructive surgery. An attempt to use homograft sclera in the feline animal model is presented. Augmentation of nasal dorsum and the chin contours was carried out in the cat model with preserved homograft sclera. Serial soft tissue radiographs and histologic study of the homografts demonstrated complete resorption of the grafts by six months. Further physical and chemical alterations of homograft sclera appear to be necessary prior to its implantation for the purpose of soft tissue augmentation.

Animals