PubMed Health⌕ Search

Biomedical subjects

R G Mitchell

Publications and source records attributed to R G Mitchell.

At least 19 recordsLinked to original sources
PubMed1992

Bacteriocin (monocin) interactions among Listeria monocytogenes strains.

Monocin interactions of 97 strains of Listeria monocytogenes were assessed using an improved production method and standardisation of the monocins against the type strain of L. ivanovii. Monocins were resistant to trypsin, sensitive to heating at 56 degrees C for 30 min and stable at 4 degrees C. Only serovar 4 strains acted as indicators. A typing system using 8 producer and 11 indicator strains showed poor discrimination.

Bacteriocins↗
PubMed1991

High mortality among patients with the leukemoid reaction and alcoholic hepatitis.

We describe a patient with severe alcoholic hepatitis, markedly elevated white blood cell count, and high fever. After review of the English literature, we discovered reports of other cases similar to our case. The striking feature in all of these cases was a high short-term mortality rate, despite predictions of a favorable outcome. We therefore believe these patients represent a subgroup of patients with alcoholic hepatitis and that the leukemoid reaction is a poor prognostic sign in this disease.

Adult↗
PubMed1991

Electro-convulsive therapy: informing patient and nurse.

Although there is still considerable controversy surrounding electro-convulsive therapy (ECT), it is widely used in psychiatric hospitals. Good nursing care is central to its successful administration, and nurses must be able to explain the procedure to patients and why it can help them.

Electroconvulsive Therapy↗
PubMed1991

Mycobacterial infections after renal transplantation.

Mycobacterial infections occurred in 11 of 633 (1.7 per cent) recipients of successful renal transplants. There were no cases of tuberculosis in patients receiving chemoprophylaxis, but amongst those who did not receive prophylaxis disease occurred in six of the 27 (22 per cent) high-risk patients. The major cause of morbidity during treatment was renal allograft rejection, largely due to reduction in immunosuppressive drug therapy.

Adult↗
PubMed1990

The long-term outcome following "special clearance" after vasectomy.

Between 1980 and 1985, 6067 out-patient vasectomies were performed under local anaesthesia at the Elliot Smith Clinic in Oxford. During this period 151 men (2.5%) were given a "special clearance". This sanctioned the discontinuation of other forms of contraception despite the persistence of scanty (less than 10,000/ml) sperm in 2 consecutively examined semen samples at least 7 months after vasectomy. These men have been reviewed and further specimens of semen requested after a minimum follow-up of 3 years (range 3-8); 50 patients supplied a specimen and all except 1 were azoospermic. No pregnancies attributable to failure of the vasectomy have been identified.

Adult↗
PubMed1989

Recurrent Listeria monocytogenes meningitis in a heart transplant recipient.

A case of recurrent Listeria monocytogenes meningitis is reported, the two episodes arising 4 months and 8 months after the patient had received a heart transplant. Both episodes immediately followed increased doses of corticosteroids for allograft rejection. The source of infection was not identified. Previous reports and possible explanations of recurrent L. monocytogenes infection are reviewed.

Heart Transplantation↗
PubMed1988

Myasthenia gravis as a cause of facial pain.

A case of myasthenia gravis is described. The diagnosis was confirmed electromyographically and immunologically; the presenting features were those of myofascial pain. Attention is drawn to the association of myofascial pain with other systemic diseases and stresses the need to look critically at the patient for evidence of a systemic origin for myofascial pain.

Adult↗
PubMed1988

Comparison of latex and haemolysin tests for determination of anti-streptolysin O (ASO) antibodies.

A latex agglutination test was compared with the micro-titration haemolysin inhibition method for the detection of anti-streptolysin O (ASO) antibodies in 428 serum samples. After slight modification of the latex method to produce maximal agglutination good agreement was shown between the results obtained by the two methods. The latex test had a sensitivity of 83.6%, a specificity of 93.3%, a predictive positive value of 86.5% and a predictive negative value of 91.6%. It was convenient, required less labour than the haemolysin test, and permitted economic testing of small numbers of sera.

Antistreptolysin↗
PubMed1987

Emericella nidulans in a maxillary sinus fungal mass.

Sexual reproductive stages of fungi are very rarely found within mammalian tissues. We report here coexistence of cleistothecia associated with Emericella nidulans and its conidial state, Aspergillus nidulans, in a fungal mass which developed in a maxillary sinus.

Aged↗
PubMed1986

Epidemiological studies using monoclonal antibodies to Legionella pneumophila serogroup 1.

Legionella pneumophila serogroup 1 can be subgrouped by panels of monoclonal antibodies. The Oxford panel divides serogroup 1 strains into three major subgroups, provisionally named Pontiac, Olda and Bellingham. Strains causing outbreaks tend to be in the Pontiac subgroup, with strains from the other subgroups appearing also in sporadic cases. Isolates from sources in the UK unassociated with outbreaks are mainly the Olda and Bellingham strains; only 10% are Pontiac, yet this strain has caused 80 to 90% of the cases of Legionnaires' Disease so far studied. We compared our method with other methods of subgrouping serogroup 1 strains.

Antibodies, Monoclonal↗
PubMed1985

Objectives and outcome of perinatal care.

Great advances in perinatal care during the past two decades have been accompanied by reduced mortality rates in progressively lower birthweight groups. Continuing effort may be warranted by these improved results or by the need to preserve human life, yet rising costs in terms of disability, stress on parents and attendants, and financial resources raise questions about the value and justification of such effort. If rational policies are to be formulated for the future, accurate data based on planned population studies are essential. Perinatal care is only one of the determinants of outcome--environmental influences are also important and must be taken into account. Resources should be directed to improving the sociocultural environment as well as the standards of perinatal care.

Critical Care↗
PubMed1985

"Agrobacterium yellow group" and Pseudomonas paucimobilis causing peritonitis in patients receiving continuous ambulatory peritoneal dialysis.

Five cases of peritonitis occurred during continuous ambulatory peritoneal dialysis in which unusual yellow pigmented Gram negative bacteria were isolated in pure culture. Four of these isolates were identified as the so called "Agrobacterium yellow group." The remaining isolate was identified as Pseudomonas paucimobilis, an organism closely related to the Agrobacterium yellow group.

Adult↗