Biomedical subjects
Publications and source records attributed to R G SCHNEIDER.
An abnormal fetal hemoglobin, designated hemoglobin F(Texas), was found in the cord blood of five Negro infants (all related and three of them siblings) and of one Caucasian infant. Studies on the chemical structure of this variant indicate that there is a substitution of a lysyl residue for either the fifth or sixth glutamyl residue of the gamma-chain.
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A new hemoglobin variant, G(couhatta) (alpha2(A) beta2(iiiglu-->ala)), has been found in three generations of a family from the Alabama Coushatta Indian tribe in east Texas. The propositus suffers from an apparently unrelated, possibly genetic, agranulocytosis. According to the history and the blood grouping data there is considerable in breeding in the tribe and remarkably little admixture with other ethnic groups.
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In an examination of the blood of 708 Eskimos, 200 Aleuts, and 44 Indians in Alaska for abnormal types of hemoglobin, only normal hemoglobin A was detected. It may be concluded that abnormal hemoglobins in these races are rare if they occur at all.
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