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Biomedical subjects

R G Sharma

Publications and source records attributed to R G Sharma.

At least 19 recordsLinked to original sources

Cancer profile in western Rajasthan.

A retrospective study of malignancy was conducted in the arid region of Western Rajasthan over a period of five years (1984 to 1988) to determine the frequencies of various malignancies. This was the region where India's first nuclear explosion took place in 1974. During this period 2662 new cancer cases were recorded. In males, Oropharyngeal and Hypopharyngeal malignancies topped the list. Males had an overall higher incidence than females (1.28:1). Most of the cases were between 31 years and 60 years with male peak at 60 years and female at 50 years. In females, cancer of the cervix formed the largest group followed by Breast cancer. A comparatively high rate of skin, urinary bladder, bone malignancy, lymphoma and leukaemia was observed in this region. Limited investigational facilities, lack of trained personnel, tough working condition, extremes of temperature, long distances in the desert region, with associated poverty, illiteracy and ignorance were some of the factors responsible for majority of the patients presenting in advanced stages.

Adolescent

Infection in burn patients.

In a recently opened burn unit which used a semi-isolation technique to treat burn patients, burn bacteriology has shown the usual pattern of bacterial cultures i.e. Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Klebsiella and proteus; with the first two predominating. Comparison with a similar study done in 1974 revealed that Streptococcus faecalis was absent in these cultures, E. coli and S. aureus infection had decreased, the number of sterile wounds had increases, there was slight increase in P. aeruginosa infection. A survey of burn wound, throat and stool cultures of patients and attendants over a 2-week period revealed pathogenic S. aureus in 3 out of 26 throat cultures. Phage typing of these strains did not reveal the same strain in any wound cultures. Similar phage type was grown from wounds in two different cabins on two different dates. thus indicating cross infection. Persistence of similar phage type was also seen in wounds of one patient. Similar aeruginocine typing of P. aeruginosa was seen in wound cultures of two different patients; one of these, type 15, was also grown in stool of the third patient thus indicating transmission of infection from the stool of one patient to the wound of other patient and from the wound of one patient to the wound of other patient.

Adolescent

Visual evoked response in macular diseases.

Visual evoked responses (VER) were recorded in 10 patients with unilateral maculopathy. VER latency and amplitude were compared between the affected and unaffected eyes. Evaluation of results reveals that in macular disease with fluid accumulation (Central Serous Retinopathy and Traumatic Macular Oedema) the VER showed amplitude reduction depending on reduced visual acuity with no significant change in latency, whereas, in disease with degeneration of retinal layers, (Degenerative Maculopathy) latency was markedly increased signifying associated conduction defect.

Adolescent