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Biomedical subjects

R G Triplett

Publications and source records attributed to R G Triplett.

50 records · Page 3Linked to original sources
PubMed1982

Experimental mandibular osteomyelitis: therapeutic trials with hyperbaric oxygen.

Hyperbaric oxygen (HBO) has been reported to be beneficial in the treatment of mandibular osteomyelitis; however, controlled laboratory studies have been limited to the long bones. In this study, osteomyelitis was created in surgically fractured rabbit mandibles by inoculation of Bacteroides melaninogenicus. Two months after inoculation, osteomyelitis was verified by bacterial cultures and inspection of the fracture sites. The animals were then randomly divided into treatment and control groups. The treatment group received HBO (2 atmospheres) for two hours daily for 40 treatment days, whereas the control group was maintained on ambient air. Although HBO therapy did not eliminate the chronic osteomyelitis, it did result in a significant improvement in sinus tract healing, osseous repair, and diminished mobility at the fracture site.

Animals↗
PubMed1981

Treatment of experimental mandibular osteomyelitis with hyperbaric oxygen and antibiotics.

Osteomyelitis was created in surgically fractured rabbit mandibles by the inoculation of Bacteroides melaninogenicus. After the disease was established, the animals were randomly divided into four groups: Group I, 16 animals, received hyperbaric oxygen (HBO) treatment alone (100% oxygen at two atmospheres pressure absolute for 2 hours daily for 40 treatments); Group II, eight animals, were untreated controls; Group III, five animals, received HBO therapy plus antibiotic treatment; and Group IV, five animals, received antibiotic treatment alone. At completion of 40 treatments, end-point assessment of the disease was performed by bacterial cultures, quantitative mobility measurements, subjective scoring, and microscopic examination of tissue to detect signs of oxygen toxicity. Mandibular osteomyelitis was not eliminated in any of the animals in this study, regardless of treatment. There was significantly greater stability in Group I (HBO treatment alone) than in Group II (untreated) animals (p less than 0.01). There was no significant difference, however, between animals in Group III (HBO and antibiotics) and Group IV (antibiotics alone) (p less than 0.05). No detrimental effects of hyperbaric oxygen therapy delivered at two atmospheres pressure for 80 h were observed.

Animals↗
PubMed1979

Quantitative radionuclide imaging for early determination of fate of mandibular bone grafts.

Clinical assessment of bone-graft healing in the maxillofacial region is generally limited to clinical evaluation, radiographs, and biopsy. A noninvasive quantitative radionuclide method has been developed in an animal model, and it seems to allow earlier prediction of graft failure or success than conventional methods. Using a localization technique to identify preselected regions of interest reproducibly in the graft and adjacent host bone, an activity ration was developed between the graft region and a contralateral control. Two mandibular grafting systems were evaluated with this technique. When the activity ratio for the graft region over the period of study approached, or was greater than, the activity ratio for the host bone, the graft subsequently proved successful by clinical observation and gross dissection. When the activity ratio for the host bone remained greater than that of the graft, healing did not occur and the grafts were unsuccessful. This method allowed prediction of graft fate by 6 wk after grafting, and preceded radiographic confirmation of repair or failure by 2-3 wk.

Animals↗
PubMedDate not supplied

The effects of preoperative resorption and jaw anatomy on implant success. A report of 303 cases.

The purpose of this paper is to report the outcome of 1097 consecutively implanted endosteal implants (Brånemark) into 303 jaws, between September 1983 and May 1990. All implants were placed using the prescribed technique suggested by manufacturer, and were restored either with fixed or removable prosthesis. Alveolar bone resorption (quantity) was scored from lesser to greater degree by assigning a value of 1-5 to each jaw, and jaw anatomy was scored from 1-4, based on decreasing cortical and cancellous bone quality. The data were separated into fixed and removable prosthesis and analyzed to determine the correlation between success and the scored resorption and jaw anatomy, as well as implant position. Assessment demonstrated a maxillary success rate of 93.4% and a mandibular success rate of 97.2% over a 36-month period (mean). Results of correlations of success with jaw anatomy for both fixed and removable prosthesis revealed that bone quality 4 exhibited the greatest failure rate. Preoperative resorption values (1-5) had little effect on failure, and quality appears to influence failure more than quantity.

Adult↗
PubMedDate not supplied

Minimizing risk of infection using a carbon dioxide laser.

The carbon dioxide laser is a surgical device increasingly important to dentistry. The advantages of laser use in the treatment of oral disease have been well documented. Such benefits include bloodless incisions, accurate tissue destruction, reduced pain, minimal swelling, excellent hemostasis, and limited postoperative tissue morbidity. Little information exists currently regarding laser use in the management of medically complex patients, most notably patients with infectious diseases. This article reports the use of the carbon dioxide laser for reducing the risks of disease transmission in the surgical management of an human immunodeficiency virus (HIV) seropositive patient.

Adult↗
PubMedDate not supplied

Implant materials, designs, and surface topographies: their effect on osseointegration. A literature review.

The aim of this article was to review the literature on materials, designs, and surface topographies of endosseous dental implants. The different categories of dental implants and the parameters of their design were analyzed in relation to their effect and significance in the process of osseointegration. The events that immediately follow implantation were described, emphasizing the factors that play a role in the development of the bone-implant interface. In addition, the methods and techniques that allow qualitative and quantitative evaluation of the interfacial zone were reviewed and their clinical correlation was assessed.

Dental Implantation, Endosseous↗