[Acute alopecia associated to empyema caused by actinomyces].
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Biomedical subjects
Publications and source records attributed to R Gómez de Tejada.
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We report the case of a 24-year-old man with a diagnosis of bronchiolitis obliterans, a rare clinical condition; the similarity to Ardystil syndrome was striking. Relevant occupational history included work in a textile air-brushing factory. Also noteworthy were lesions observed by CT scan in the form of cystic formations measuring less than 1 cm, a finding not previously described in the context of bronchiolitis obliterans. The patient improved immediately after starting corticoid treatment although scans failed to improve over several months of follow-up.
Though there are not many cases described in the literature and very few for children, the existence of lower urodigestive communications may give rise to inflammatory processes in gonads and gonaducts in the male. We have carried out an experimental study of this aspect on 248 male Wistar rats according to the following design: A 48 animal control group (C) is divided into four equal subgroups sacrificed at the ages of one, two, three and four months. The problem group (P) of 200 animals are all submitted to vesicosigmoidostomy and then 100 are sacrificed after one and two months, and the other 100 are dis-diverted one and two months after the original diversion and sacrificed one month later. No histological alterations were observed in gonads and gonaducts for the sacrificed control animals (n = 48). The animals sacrificed after diversion (44 per 100) showed the following histological alterations: five cases of testicular tube necrosis, two cases of deferent conduit inflammation, one case of deferent conduit necrosis, 12 cases of epididymis inflammation and 13 cases of epididymis necrosis. The animals that also underwent dis-diversion and that were later sacrificed (20 per 100) showed: five cases of testicular tube necrosis, one case of testicular inflammation, two cases of deferent conduit inflammation, four cases of epididymis inflammation and seven cases of epididymis necrosis. Statistical analysis showed that the differences between the two P groups were not significant.(ABSTRACT TRUNCATED AT 250 WORDS)
We have carried out an experimental model of urinary diversion and dis-diversion on male Wistar rats in order to study the complications that are produced after diversion, as well as to see whether the alterations continue unchanged, or increase, or diminish after dis-diversion. The following experimental design was used: a control group made up of 48 animals an a problem group of 200 animals all submitted to vesicosigmoidostomy of which 100 were designed to be subsequently dis-diverted. The sacrificed animals (n = 112) were studied for somatic, biochemical and histological parameters. Statistical comparison of the problem group with the controls showed significant differences for the somatic and biochemical parameters, especially in the form of weight-size retardation, increase of urea, creatinine, calcium, phosphorus, uric acid, cholesterol, transaminase, alkaline phosphatase, sodium and chlorine and decrease in albumin and total proteins. After dis-diversion there is an improvement of some of these parameters without reaching total normalization. This leads us to think that either the lesions are irreversible, or more time after dis-diversion is needed for there to be reversibility. We also describe the histological lesions found at the level of the vesicointestinal anastomosis, and the mortality of our series which is higher than that presented by females, a fact inducing us to think that factors exist in the male which increase the mortality.
The present experimental study was carried out in 75 female Wistar rats. End-to-side vesicosigmoidostomy was performed in 65; the remaining 10 rats comprised the control group. Thirty-three rats were de-diverted at 1 and 2 months later. The site of the vesicosigmoid anastomosis was assessed histologically at 1, 2, and 3 months postoperatively in diverted rats, and at 1 and 2 months in de-diverted rats. Squamous metaplastic changes and variable degrees of transitional cell line neoplasm were observed in the diverted rats. Bladder changes did not regress significantly after de-diversion. No structural changes were observed at the level of the sigmoid. This experimental animal model confirms the oncogenic potential of mixing feces and urine, and shows that de-diversion does not achieve significant regression of bladder tumor lesions.
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This paper is a review of 63 cases of congenital Pyeloureteral Union Syndrome. A total of 47 patients were treated using the Anderson-Hynes reconstructive technique with 3-4 years follow-up. Incidence was analyzed by sex, age and side affected, without a clear predominance of one over the others being shown. Mean age at the time of diagnosis was 39-43 years. The predominant symptom is the presence of lumbo-abdominal pain (36.5%) but the lack of clinical symptoms is also frequent (25.3%). Pyelocalyceal lithiasis is the most frequent secondary pathology (28.5%). U.I.V. appears to be an irreplaceable means for diagnosis, achieving with this technique 93.6% of diagnosis. Hydronephrosis, in different degrees, and absence of ureteral contrast are the urographic signs most commonly found: 66% and 61% respectively. Using the Anderson-Hynes technique a rete of 85% good results can be obtained, with few complications and achieving disappearance of clinical symptoms and morphofunctional normality in a high percentage. Anderson-Hynes dismembered ureteropyeloplasty seems to be the choice technique for conservative surgical treatment of the P.U.U. syndrome.
Another two cases of bladder adenocarcinoma (ADC), seen in 1988, are described herein. The most important aspects relative to tumor origin--urothelial and embryonal--are discussed. We review its clinical features and diagnosis, not unlike those of transitional cell tumors, although histologically different. We underscore the therapeutic aspects and poor prognosis in most of the cases.
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