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Biomedical subjects

R García-Guasch

Publications and source records attributed to R García-Guasch.

15 recordsLinked to original sources
PubMed2000

[Publications derived from free communications at the XX Congress of the Anesthesiology and Resuscitation Spanish Association (Anesthesia 92)].

OBJECTIVES: To analyze the publication in MEDLINE-indexed journals of articles derived from free presentations at the Twentieth Congress of the Spanish Society of Anesthesiology (SEDAR) (Anestesia 92) held in 1992. MATERIAL AND METHODS: Two of the authors independently investigated the publication of research presented at Anestesia 92 in MEDLINE-indexed journals, carrying out a search of authors' names between 1990 and 1998 with no restrictions on language or type of publication. We obtained year of publication and names of journals and extracted the abstracts, then analyzing the number and order of authors, content and time elapsing between the congress and publication. RESULTS: Eighty-four articles (17.1%) were published based on 491 congress presentations, with a mean time to publication of 1.8 years (range -2 to 6). Journals specializing in anesthesiology published 79.8%, and Revista Espanola de Anestesiología y Reanimación published 59.5%. Different authors were listed for published articles and congress presentations in 92.9% and the first author had changed in 35.7%. The content of a published article was similar to that of the congress presentation in 46% and scope was reduced for publication in 35.7%. CONCLUSIONS: Few publications were derived from free presentations at Anestesia 92 and major changes were made in authors and content between congress presentation and publication.

Anesthesiology↗
PubMed1998

[Diltiazem compared with placebo in the prevention of myocardial ischemia during non-cardiac surgery].

OBJECTIVE: The aim of this study was to assess the efficacy and safety of intravenous diltiazem to prevent myocardial ischemia during surgery on patients with ischemic heart disease undergoing non cardiac surgery under general anesthesia. PATIENTS AND METHOD: Sixty patients scheduled for elective non cardiac surgery under general anesthesia were randomly assigned to two groups to receive diltiazem or placebo under double blind conditions. After an intravenous dose of 0.15 mg/kg of diltiazem or an equivalent amount of placebo, an infusion of 3 micrograms/kg/min of diltiazem or placebo was begun and continued until three hours after surgery. Thirty minutes after starting the infusion, anesthesia was induced by 0.1 mg/kg diazepam, 3 micrograms/kg of fentanyl and 0.3 mg/kg of etomidate. Intubation followed administration of 0.6 mg/kg of atracurium. Anesthesia was maintained with N2O/O2 and halothane and was the same for both groups. DII and V5 leads were monitored on a Cardiowiss CM-8 ECG machine that allowed us to set the alarm when ST segment variations reached 1 mm above or below baseline. We analyzed the number, intensity and duration of ischemic episodes recorded, as well as hemodynamic variables and side effects. RESULTS: Data for 46 patients were valid. At least one ischemic episode was experienced by 15% of patients in the placebo group and 1 in the diltiazem group (p < 0.05). The episodes were related to increased systolic arterial pressure (p = 0.04). ST segment decreases were 1.1 to 3.6 mm (1.75 +/- 0.7) (mean +/- SD) and lasted between 1 and 45 minutes (11.62 +/- 13.26) (mean +/- SD). No significant side effects were observed. CONCLUSIONS: Intravenous diltiazem administered to patients with ischemic heart disease under general anesthesia for non cardiac surgery was effective in our study for preventing intraoperative ischemic episodes.

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