Biomedical subjects
Publications and source records attributed to R Garcia de Sola.
We present a type 1 neurofibromatosis case with sarcomatous degeneration of a cranio-orbital neurofibroma, its surgical evolution and the cytogenetics and cellular proliferative potential features (CMF, Ki-67 antibody).
Treatment of vertebral epidural metastases has been in the past and still remains the object of special attention in an attempt to improve the quality of life of these patients. To assess the effects of and indications for surgery, the clinical histories of 53 patients with this malignant disease who had undergone decompressive laminectomy have been reviewed retrospectively. The importance of the presence of complete or partial spinal cord compression in correlation with the presence of complete or partial myelographic block is dealt with. The results concerning pain, gait disturbances and sphincter disorders are studied with respect to the clinical and myelographic picture for the purpose of establishing the indications for decompressive laminectomy. Pain is not an indication for operative decompression, and complete paraplegia always never improves, thus being a contraindication. But in incomplete spinal cord involvement a decompression operation may be followed by an improvement of neurological deficit and quality of life.
The authors present one case of a 42 years old male patient who had a small right paraventricular arteriovenous malformation. At operation the patient was placed in the Talairach's stereotactic frame and, after performing a right carotid angiogram to locate the lesion exactly, a flexible cannula was inserted stereotactically, through a previous trephine hole, until the tip reached the AVM. Using a microsurgical technique and through a 1-2 cm corticotomy the cannula pathway was followed easily reaching the AVM. Total removal of the AVM was confirmed by a carotid angiogram, the patient was discharged without symptoms 7 days later. The authors propose that due to the special design of the Talairach's stereotactic frame, its application as a locating system for small and deep AVM's would greatly facilitate their removal using microsurgical techniques.