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R Genin

Publications and source records attributed to R Genin.

36 records · Page 2Linked to original sources
PubMed1982

[Cholesterol embolisms. The anatomical, clinical and pathogenetic aspects. Two case reports, including one case of pseudo periarteritis nodosa (author's transl)].

The authors report on two cases of cholesterol embolism, with one masquerading as polyarteritis nodosa. Cholesterol embolism is a frequent but often unrecognized complication of ulcerous athero-sclerosis. Atherosclerotic foci release a large quantity of cholesterol crystals, spontaneously or after endovascular manipulations, inducing the obstruction of small arteries, 150 to 200 microns in diameter, in various organ or tissues of the organism, such as the kidneys, the spleen, the pancreas, the digestive tract, the skin and the retina. Cutaneous, muscular, reno-vascular and visceral forms have been described, based on the distribution of the crystals. This disease, with its multiple systemic localisations and biological abnormalities may sometimes be confused with polyarteritis nodosa and constitutes the pseudo-PAN form of cholesterol embolism. In all these cases, the simplest method of diagnosis consists in the examination of the fundus and in the analysis of skin and muscle biopsies. Finally, the features of the arteriolar lesions and the lack of immunological disturbances suggest that cholesterol embolisms are form of microcrystalline arteriopathy.

Arteriosclerosis↗
PubMed1979

Pulmonary metastatic calcification with respiratory insufficiency in patients on maintenance haemodialysis.

A uraemic patient undergoing chronic haemodialysis developed diffuse metastatic pulmonary calcification and died from acute respiratory insufficiency after renal transplantation. Thirteen similar cases previously published are reviewed, with emphasis on the clinical and anatomical features of such calcinosis. The pathogenesis of this calcification in patients on maintenance haemodialysis and some rules for its prevention are discussed.

Adolescent↗
PubMedDate not supplied

[Anatomo-clinical features of Castleman tumour. Report of a case with a membrano-proliferative glomerulonephritis (author's transl)].

A case of retro-peritoneal lymphoid angio-follicular hyperplasia or Castleman's pseudo-tumour with normochromic hormocytic anemia and membrano-proliferative glomerulonephritis is reported in a 53 year-old man. Since the first description by Castleman in 1954, 259 other cases have been published. The anatomo-clinical study of our observation and of 198 cases collected in the literature bears out 3 types of clinical forms, according to the location of the pseudo-tumour: mediastinal, superficial and abdominal. The first ones generally asymptomatic are the most frequent whereas the last ones, less common, are often associated with biological abnormalities. In spite of these differences such neoformations present the same morphologic features. They are round or ovoid and well delimited by a capsule. Under this capsule a lymphoid vascular tissue surrounds follicules with central capillaries or arterioles. When plasma cells infiltrate the stroma, perturbations such as anemia or hypoalbunemia appear. Besides a nephrotic syndrome has been discovered in our observation and in that of Humpherys. In all the cases the removal of the pseudo-tumour induces the retrogression of the biological abnormalities and of the nephrotic syndrome. Neither a recidive nor another location of the disease are noticed later on. This evolution is probably the fact of a benign hyperplatic process which grows after an antigenic stimulation.

Abdomen↗