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Biomedical subjects

R Gergely

Publications and source records attributed to R Gergely.

5 recordsLinked to original sources
PubMed1978

Oral contraceptives and focal nodular hyperplasia of the liver. Two case reports with electron-microscopic studies.

The authors report on the cases of 2 young females who had been on oral contraceptives for 2 and 6 years, respectively. During cholecystectomy, as a subsidiary finding, liver tumour was found which, histologically, proved to be focal nodular hyperplasia. On the basis of their electron-microscopic studies, they consider possible the primary role of pathological vascularization in the development of the tumour. They suggest the radical removal of the tumour and regard as inevitable for the patient the stopping of oral contraceptives, due to the recurrence or malignant transformation of the tumour.

Basement Membrane↗
PubMed1977

[Primary carcinoma of the liver and long-term administration of oral contraceptives followed by pregnancy (author's transl)].

A 32-year-old woman who had taken oral contraceptives for seven years, became pregnant after omitting the drug and had a normal child. Soon after a malignant hepatic tumour became apparent of which she died after three months. The tumour was a hepatocellular carcinoma, of low differentiation under the electron microscope. The tumour cells contained fibrils similar to alcoholic hyaline. A review of published reports suggests the possibility that the oral contraceptives and the hormonal influence of the pregnancy together played an important role in the development of the malignant tumour.

Adult↗