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Biomedical subjects

R Gershon

Publications and source records attributed to R Gershon.

9 recordsLinked to original sources
PubMed2001

The risk of acquiring hepatitis B or C among public safety workers: a systematic review.

CONTEXT: Determination of the occupational risk of hepatitis B and C to public safety workers is important in identifying prevention opportunities and has significant legal and policy implications. OBJECTIVES: Characterize the risk of occupationally acquired infection: (1) risk of exposure to blood and body fluids, (2) seroprevalence of hepatitis B and C in the source population, and (3) risk of infection after exposure. DATA SOURCES: Electronic search of MEDLINE (1991-1999), HealthStar (1982-1999), and CINAHL (1975-1999) supplemented by selected reference citations and correspondence with authors of relevant articles. STUDY SELECTION: Peer-reviewed journal articles (N=702) that addressed the transmission of hepatitis B and C in law enforcement, correctional, fire, emergency medical services, and healthcare personnel were identified. One hundred five (15.0%) articles were selected for full-text retrieval; 72 (68.6%) were selected for inclusion. DATA ABSTRACTION: Articles selected for inclusion were abstracted by two reviewers and checked by a third reviewer, using a standard reporting form. DATA SYNTHESIS: Evidence tables were constructed, using the standardized abstracts. The tables were designed to summarize data for the key elements of the risk analysis. CONCLUSIONS: Data suggest that emergency medical service (EMS) providers are at increased risk of contracting hepatitis B, but data have failed to show an increased prevalence of hepatitis C. EMS providers have exposure risks similar to those of hospital-based healthcare workers. Other public safety workers appear to have lower rates of exposure. Urban areas have much higher prevalence of disease, and public safety workers in those areas are likely to experience a higher incidence of exposure events.

Blood-Borne Pathogens↗
PubMed2000

CAT administration of language placement examinations.

This article describes the development of a computerized adaptive test for Cegep de Jonquiere, a community college located in Quebec, Canada. Computerized language proficiency testing allows the simultaneous presentation of sound stimuli as the question is being presented to the test-taker. With a properly calibrated bank of items, the language proficiency test can be offered in an adaptive framework. By adapting the test to the test-taker's level of ability, an assessment can be made with significantly fewer items. We also describe our initial attempt to detect instances in which "cheating low" is occurring. In the "cheating low" situation, test-takers deliberately answer questions incorrectly, questions that they are fully capable of answering correctly had they been taking the test honestly.

Aptitude Tests↗
PubMed1996

Methodologic issues in intervention research--health care.

To better understand the methodological challenges faced by intervention research in health care, workshops reviewed two intervention studies to reduce back injuries among nursing home staff and two studies on the use of precautions to prevent occupational transmission of bloodborne pathogens. These studies adapted rigorous designs to real-world settings and made good use of multiple measures to detect effects and communicate this information to policy makers. The studies grappled with issues about implementation integrity and would benefit from better theory of administrative practices associated with a safety-conscious work environment.

Back Injuries↗
PubMed1996

Facilitator report: bloodborne pathogens exposure among health care workers.

Several psychosocial and organizational factors have been identified as important correlates of compliance with safe work practices among health care workers. In particular, compliance with "universal precautions"--a set of work practices which were designed to minimize exposure to bloodborne pathogens--has been found to be associated with several potentially modifiable factors. The development of interventional strategies designed specifically to target these factors (e.g., HIV/AIDS attitudes, safety climate) are important objectives in the overall risk management approach to occupational exposure to bloodborne pathogens.

Acquired Immunodeficiency Syndrome↗
PubMed1986

Ambient illumination and the determination of material changes.

The task of distinguishing material changes from shadow boundaries in chromatic images is discussed. Although there have been previous attempts at providing solutions to this problem, the assumptions that were adopted were too restrictive. Using a simple reflection model, we show that the ambient illumination cannot be assumed to have the same spectral characteristics as the incident illumination, since it may lead to the classification of shadow boundaries as material changes. In such cases, we show that it is necessary to take into account the spectral properties of the ambient illumination in order to develop a technique that is more robust and stable than previous techniques. This technique uses a biologically motivated model of color vision and, in particular, a set of chromatic-opponent and double-opponent center-surround operators. We apply this technique to simulated test patterns as well as to a chromatic image. It is shown that, given some knowledge about the strength of the ambient illumination, this method provides a better classification of shadow boundaries and material changes.

Color↗
PubMed1982

Microenvironmental immunoregulation: possible role of contrasuppressor cells in maintaining immune responses in gut-associated lymphoid tissues.

The addition of Peyer's patch T cells from most strains of mice to spleen cells in primary Mishell-Dutton cultures either has no effect or augments the spleen cells' response to sheep erythrocytes. However, if the Peyer's patch T cells are treated with an anti-I-J antiserum and complement to remove contrasuppressor-inducer cells, the remaining Ly-2 cells (T cells that express Ly-2 but not Ly-1) are highly suppressive. This "latent" suppressor cell activity also can be revealed by removing contrasuppressor-acceptor (transducer) cells from the splenic assay population with either an anti-I-J or anti-Ly-2 antiserum. These findings, taken together with previous work showing that orally administered antigen leads to systemic tolerance, give experimental support to the notion that contrasuppression may be important in allowing microenvironmental immune responses (in this case the gut-associated lymphoid tissue) to take place while systemic immunity is suppressed.

Animals↗
PubMed1980

Suppressor cells in vitro: differential effects of indomethacin and related compounds.

In vitro immune response systems known to involve suppressor cell regulation were examined for effects produced by the drug indomethacin and other compounds known to inhibit the cyclooxygenase pathway of arachidonic acid metabolism. In all cases tested where suppressor T cell activity is known to be the dominant inhibitory mechanism, suppression was not blocked by drug addition and was sometimes more pronounced. In the cases tested where suppression could be attributed to a non-T cell, most likely a macrophage-like cell (M0), suppression could be abolished by drug treatment. Indomethacin and related compounds may be useful analytical tools for separation of T cell vs. non-T cell mediated suppression.

Animals↗
PubMedDate not supplied

Testing the reliability and validity of a measure of safety climate.

The lack of compliance with universal precautions (UP) is well documented across a wide variety of healthcare professions and has been reported both before and after the enactment of the Occupational Safety and Health Administration's Bloodborne Pathogens Standard. Gershon, Karkashian, and Felknor (1994) found that several factors correlated significantly with healthcare workers' lack of compliance with UP, including a measure of organizational safety climate (e.g., the employees' perception of their organizational culture and practices regarding safety). We conducted a secondary analysis using data from a cross-sectional survey of a convenience sample of 1,746 healthcare workers at risk of occupational exposure to bloodborne pathogens to assess the validity and reliability of Gershon's measure of safety climate. Findings revealed no relationship between safety climate and employees' gender, age, education, tenure in position, profession, hours worked per day, perceived risk, attitude toward risk, and training. An association was demonstrated between safety climate and (1) healthcare worker compliance with UP and (2) the availability of personal protective equipment, providing support for the construct validity of this measure of safety climate. These findings could be used by occupational health professionals to assess employees' perceptions of the safety culture and practices in the workplace and to guide the institution's risk management efforts in association with U.P.

Adult↗