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R Goerg

Publications and source records attributed to R Goerg.

33 records · Page 2Linked to original sources
PubMed1979

[Hemodynamic studies during temporary, unilateral occlusion of the pulmonary artery (author's transl)].

During pre-operative evaluation of 35 patients prior to pulmonary resection, pressure measurements in the right heart and pulmonary circulation were performed. In addition to pressure values, pulmonary ventilation and partial pressures of the blood gases were assessed before and during unilateral occlusion of the pulmonary artery at rest and during exercise. Statistically significant increased values from regression analysis were obtained for mean pulmonary artery pressure, right ventricular end-diastolic pressure, pulmonary vascular resistance and right ventricular work. The results show that plethysmorgraphic and ergometric studies as well as their combination with blood gas analysis, are not indicative of changes in right ventricular or pulmonary arterial hemodynamics. Prior to pulmonary resection, catheterization should be performed at rest and during exercise to assess these variables.

Adult↗
PubMedDate not supplied

Treatment of malaria tropica with a fixed combination of rifampicin, co-trimoxazole and isoniazid: a clinical study.

The treatment of malaria tropica is becoming difficult because of the increasing drug resistance rates of Plasmodium falciparum against several of the currently available antimalarias. A fixed combination of rifampicin, co-trimoxazole and isoniazid (CotrifazidTM, CF) was found to be highly effective for the treatment of malaria tropica. The aim of the present study in Kenya was to scrutinize this finding in a 14-day trial. Patients with malaria tropica were given in an open, double-arm randomized study CF for 5 days, or chloroquine or pyrimethamine/sulphadoxine as the control. Because of an apparently better activity and tolerance of CF, the randomization had to be stopped after the enrollment of 50 patients. A total of 61 patients in both groups (35 of them between 2 months and 6 years of age) were available for final analysis. All 41 patients treated with CF, originally positive in their blood smears, turned negative; in 2 cases blood smear positivity reappeared on day 14. There were 7 failures in the control group, 4 of them a primary one. Four of those failures were turned negative with CF, 2 failed with CF also, and 1 disappeared. The tolerance of CF was excellent even in infants. In our experience, CF is very well suited for the treatment of malaria tropica, also in cases of apparent drug resistance of P. falciparum against other antimalarials, and even in severe cases of the disease.

Age Distribution↗