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R Golz

Publications and source records attributed to R Golz.

10 recordsLinked to original sources
PubMed1997

Appendix carcinoma invading the urinary bladder.

We report a case of an appendix carcinoma invading the urinary bladder. In contrast to other bowel tumors invading the bladder, history and symptoms were consistent with a primary bladder tumor. This is due to the unique anatomical position of the appendix where the tumor did not hinder passage of bowel contents or cause melena. Findings on physical examination as well as diagnostic imaging and transurethral resection were inconclusive. Consideration of local progression of an appendix carcinoma is an important differential diagnosis. In contrast to other vesical or extravesical T4 tumors, the appendix carcinoma offers a good chance for resection en bloc by right-sided hemicolectomy and partial cystectomy.

Adenocarcinoma, Mucinous↗
PubMed1994

Ultrastructure and molecular composition of the central filament body in hydrozoan cnidocils.

The cnidocils of hydrozoan nematocytes contain modified microtubular axonemes and a cross-striated central filament body. Filament body and axonemal microtubules are interconnected by cross-bridges or are directly attached to one another. Structure and molecular composition of the central filament body was analyzed by means of electron microscopy and immunological techniques. The spindle-like, cross-striated filament body is composed of less than 4 nm thick subfibers. Each unit of its periodical striation pattern is approximately 19 nm broad and comprises subzones with different electron densities. Pure filament bodies are obtainable by a lysis of isolated cnidocils in detergent- and EDTA-containing buffers. The filament body is soluble in 5 mM dithioerythritol (DTE) or 1 M urea. Its structure is stabilized by high concentrations of Na+ or K+ (0.5 M both). Intermediate states of assembly can be induced by 1 mM DTE in lysis buffer which causes the filament bodies to spread into subfibers. CFB43, a monoclonal antibody against filament body protein reacts with a 33 kDa protein in Hydra. Like a polyclonal antibody against SF-assemblin, the protein forming cross-striated system I fibers in unicellular green algae, the antibody cross-reacts with a 36 kDa protein obtained from the unicellular organism Tetrahymena. In immunogold labeling experiments, CFB43 binds to the central filament body in Hydra and recognizes an epitope on the striated rootlets associated with the basal bodies of Tetrahymena. Our results indicate that the central filament body of hydrozoan cnidocils is composed of a protein with properties similar to those of SF-assemblin. In combination with microtubules, the filament body seems to participate in the formation of a stiff mechanical backbone within the cnidocils.

Animals↗
PubMed1993

Mutants with substitutions for Glu171 in the catabolite activator protein (CAP) of Escherichia coli activate transcription from the lac promoter.

Single amino acid substitutions for residue Glu171 in helix E of the catabolite gene activator protein (CAP) of Escherichia coli have been reported to abolish activation of transcription without impairing binding to the CAP site of the lac promoter. The negative charge of Glu171 was proposed to transmit the activating signal from CAP to RNA polymerase. However, this idea has been challenged by later work. We set up a system to re-examine this issue. We analysed the ability of mutant CAP-E171L and CAP-E171K proteins to bind a near-consensus CAP site in vivo and found it to be diminished fourfold relative to wild type in each case. Activation of lac transcription by these mutant proteins remains the same as with wild-type CAP. Thus our results confirm that Glu171 in helix E of CAP is not involved directly in the activation of transcription. Yet CAP-E171K does not activate transcription as well as wild-type CAP under all circumstances. Possible reasons for this absence of activation are discussed.

Amino Acid Sequence↗
PubMed1992

Sequential infection of silicone metacarpophalangeal joint arthroplasties resulting from skin breakdown.

We report a case of late multiple infected metacarpophalangeal silicone implants in a patient who had had replacement arthroplasty for treatment of rheumatoid arthritis. The patient had done well for 10 years after metacarpophalangeal joint arthroplasty when an implant infection developed. Over the next 4 years the remaining three implants on her dominant extremity also became infected necessitating their removal. The origin of the infections is thought to be the result of excessive and improper usage of the hand.

Arthritis, Rheumatoid↗
PubMed1992

Frequency of urogenital tuberculosis in an unselected autopsy series from 1928 to 1949 and 1976 to 1989.

The evaluation of a total of 12,211 autopsy protocols prior to the introduction of chemotherapy (1928-1949) and in the recent years (1976-1989) had the following results: the frequency of renal tuberculosis has dropped from 2.0 to 0.6% of all autopsies in men and from 1.7 to 0.9% in women. While the frequency of miliary tuberculosis infections in general has decreased to about one fourth (from 2.7 to 0.6% of all autopsies), renal involvement in patients with miliary tuberculosis has rather increased (from 35.4 to 52.2 for men and from 37.5 to 68.0% for women). The frequency of miliary tuberculosis of the kidneys was two times higher in girls than in boys (3.8% of girls and 1.8% of boys). Tuberculosis of the renal pelvis, ureter or urinary bladder secondary to a renal tuberculous infection has decreased from 65 to 4.3% of all tuberculous infections with renal involvement in males and from 25 to 0% in females. In the second period, the frequency of genital tuberculosis has in all dropped to about one tenth.

Adult↗
PubMed1992

[Intrauterine pericardial effusion. Early symptom of a primary symptomatic congenital cytomegaly].

We report of a fetus who was ultrasonographically shown to have growth retardation, oligohydramnios and a pericardial effusion without other components of a hydrops fetalis at 28 weeks' gestation. At 29 weeks' gestation the child was born by cesarean section of pathological CTG. A congenital cytomegaly was diagnosed. The etiological role of the infection for the development of the pericardial effusion is discussed.

Adult↗
PubMed1989

Prostatic specific antigen: immunoreactivity in urachal remnants.

Urachal remnants were obtained at autopsy from 10 males and 15 females in order to determine whether prostatic specific antigen (PSA) is present in that tissue. Immunohistochemical staining was carried out using a commercially available antibody to PSA. Four cases (three females and one male) showed focal positive reaction of PSA, predominantly in narrow glandular structures of metaplastic origin. Therefore, it cannot be excluded that PSA might occur in urachal adenocarcinomas. PSA-staining is evidently not confined exclusively to tissue originating in the prostate.

Adenocarcinoma↗
PubMed1988

Multifocal adult rhabdomyoma. Case report and literature review.

Extracardiac adult rhabdomyoma is a rare benign tumor which occurs mostly in the head and neck region. A few cases of adult extracardiac rhabdomyoma (9 out of 69 reported) have been multifocal. We present a new case of multifocal adult rhabdomyoma which was asymptomatic. We describe histological features of adult rhabdomyoma which may provide a means for distinguishing it from other types of tumors.

Aged↗
PubMedDate not supplied

Candidosis of the prostate: a rare form of endomycosis.

The third case of a culturally and histologically proven candidosis of the prostate in the world literature available to us is reported. Autopsy of a 59-year-old man with metastasizing bronchial carcinoma as predisposing primary disease revealed a local candidosis of the prostate in the left lobe of the prostate, without evidence of a Candida sepsis. Parallel and different aspects in comparison with the other two cases are described.

Candidiasis↗