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R Goodall

Publications and source records attributed to R Goodall.

9 recordsLinked to original sources

Development of a high performance zinc-62/copper-62 radionuclide generator for positron emission tomography.

Clinical utilisation of positron emission tomography could be enhanced by the availability of short-lived radionuclides derived from generator systems. The zinc-62/copper-62 combination is one such system which could be used as a source for a number of copper-62 radiopharmaceuticals. We have developed and optimised a high activity (5.6 GBq, 150 mCi) zinc-62/copper-62 generator to provide 62Cu in a form that is suitable for direct labelling of pyruvaldehyde-bis-(N4-methylthiosemicarbazone)-copper(II), Cu(PTSM). The distribution coefficients of Zn(II) and Cu(II) between anion-exchange resin and various hydrochloric acid/organic solvent mixtures were measured. Based on these measurements a generator eluent of 0.3 M HCl/40% ethanol provided 62Cu in greater than 90% yield in a 3-ml volume. A very low 62Zn breakthrough of less than 3 x 10(-7)% was achieved. Copper-PTSM was successfully labelled with the no-carrier-added 62Cu eluent directly from the generator with 94% radiochemical yield.

Copper

Democratic management principles. Involving the staff in decision making.

Participative management is consistent with our history and culture, and it can often improve morale and productivity among hospital staff. Participative management, however, is not a panacea, nor is it necessary for managerial success. It should be used with discretion, following some of the guidelines outlined in this article.

Decision Making, Organizational

Managing problem performance. A supervisor's responsibility.

Following the suggestions in this paper will not guarantee that you will never have discipline problems or that you will deal with them effectively every time they arise. But the OR supervisor who provides good orientation, sets clear goals and standards, and who consistently motivates employees through foresight, praise, and encouragement should have fewer discipline problems. And if the supervisor develops the self-knowledge, communication skills, and administrative capabilities described in this paper, he or she should be able to cope with unavoidable problems more effectively.

Communication