Clinical effect of O-betahydroxyethyl-rutosides (HR) in patients with occlusive arterial disease.
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Biomedical subjects
Publications and source records attributed to R Grabowski.
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The influence of stanozolol Stromba and phenformin Dibotin (Winthrop) and complamin (Wulfing) on transformation of 131J-fibrinogen administered intravenously was examined in 39 patients with arteriosclerosis obliterans. The patients were divided into 3 groups; one of the groups included untreated patients. Radioactivity of the plasma and of the urine was determined by means of a scintillation counter. The volume of plasma, plasma fibrinogen (g%, g, g/kg), half time of persistance (T 1/2) and degradation of fibrinogen were determined. The patients who received Dibotin and Stromba simultaneously showed statistically significant decrease of the plasma fibrinogen degradation im comparison to the control group. But in patients who received complamin in spite of significant decrease of the plasma fibrinogen (g%), the fibrinogen degradation was not different from the value obtained in the group.
There is now a general concensus of opinion that the specific care of patients with congenital clefts should be performed in the framework of their rehabilitation in large centres. The values of timely and competent care is deduced from results obtained from 100 orthodontic patients. In cleft patients orthodontic treatment must begin several years earlier than in patients without clefts.
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On the basis of the findings from 1470 patients referred for orthodontic treatment, the authors analyse, for various types of anomalies, the sequelae of untreated proximal caries and premature extractions in the supporting areas of the upper and the lower jaw. The results obtained indicate that the premature loss of deciduous teeth causes, in case of malalignment associated with lack of space, secondary alterations.
This paper recommends that the development of deciduous teeth in patients with extensive unilateral clefts should be studied by reference to jaw models and compared with results obtained by Heckmann in a series of investigations of regular sets of deciduous teeth and that such studies should be made on the model of those which were conducted, in recent years, by workers at the Rostock Department of Orthopedic Stomatology and which were concerned with questions associated with the normal development of dentures.
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