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Biomedical subjects

R Griffo

Publications and source records attributed to R Griffo.

31 records · Page 2Linked to original sources

[Early ergometric test and rehabilitation after myocardial infarct in young adults: results and prognostic significance].

A maximal, symptom-limited exercise test was performed 4 weeks after an acute myocardial infarction in 108 subjects aged less than 40. All the patients were afterwards engaged in a 6 weeks supervised rehabilitation program. Following the rehabilitation, 99 patients underwent programmed controls for a mean period of 23.4 +/- 16 months. Anamnestic data, site of the infarction, early exercise test response, rehabilitation results were statistically evaluated. They were compared with the follow-up data to estimate their predictive value of late cardiac events. Only the exercise testing data were found to be of prognostic significance. In fact, 77.8% of patients with ischemic response to the test had new cardiac events in the follow-up period. The percentage of late cardiac events was 26.7% in patients with hypotensive response and 8.4% in patients with normal response. The ischemic response was found to be more frequent in patients with inferior myocardial infarction. The highest rate of new cardiac events (86%) occurred in patients with inferior infarction and ischemic response to the early exercise test. An early exercise test seems to be of value to assess the prognosis after a myocardial infarction in young men. An ischemic response is a reliable sign of a poor prognosis; on the other hand, a normal response to the test does not exclude the possibility of late cardiac events, which may occur in about 10% of these patients.

Adult↗

[Prinzmetal's angina initiated by interruption of exercise. 5 cases with normal coronary radiograms].

Five male patients, aged between 31 and 58 years, presented with anginal chest pain with nausea and sweating after the interruption of exercise. Prinzmetal variant angina was observed during the recovery phase of exercise tolerance testing. Coronary arteriography and selective left ventricular angiography were normal in all cases. Ergonovine, used in one case, induced coronary artery spasm. The angina was eased by Nifedipine in three patients and passed off with time in the other two patients. In one case attack occurred with amiodarone therapy and in another with glyceril trinitrate, after normal exercise tolerance tests. Vagotonia, all the more pronounced when sympathetic tonus is increased, and hyperventilation seem to be the causative factors of what probably results from coronary artery spasm. Nifedipine, a calcium-blocking agent would appear to be the treatment of choice.

Adult↗