Serum urate level and cancer.
Histograms of the serum uric acid level of cancer patients (n = 501) and healthy controls (n = 15150) are compared. The statistical evaluation of the data yields significantly lower uric acid levels for cancer patients than for healthy persons (P less than 0.0001 for males, P less than 0.001 for females). These results support the theory that reactive species of oxygen (singlet oxygen and oxygen radicals) play an important role during carcinogenesis.
Adult↗