Re: Genetic susceptibility of benign prostatic hyperplasia.
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Biomedical subjects
Publications and source records attributed to R H Burger.
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Radionuclear imaging of micturition (RNIM) (Nuclear Uroflowmetry, Voiding Nuclear Cystogram) measures bladder volumes, bladder emptying times, and urinary flow rates. These data help to differentiate normal subjects from those with obstructive uropathy or neuromuscular failure and to quantify the deficit. We discuss the physiological considerations of importance to physicians ordering and interpreting this convenient and noninvasive diagnostic procedure.
The increased use of intracorporeal drugs in the treatment of impotence has advanced our understanding of erectile physiology. Radionuclide imaging of the penis (nuclear penogram) has provided clinicians with a noninvasive, objective measure of blood flow and blood pool changes during erection and with assistance in the quantitative documentation of therapeutic effect.
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Fifty-six type II diabetic males (mean age 52) were studied. Nineteen (33.9%) were diagnosed as having secondary impotence (SI); there was no correlation with age, diabetic control, and the use of insulin versus oral antidiabetic agents. Positive correlation was found between slow (less than 42 M/sec) motor nerve conduction velocity (MNCV) and SI at p less than 0.02, amounting to 58 per cent of the 19 cases. SI did not correlate with a standard list of peripheral neuropathic symptoms alone in the absence of slow MNCV. Correlation with SI was greatest when slow MNCV coexisted with neuropathic symptoms (p less than 0.04). MNCV testing may improve diagnosis and cost-effectiveness in assessing diabetic men with impotence.
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