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Biomedical subjects

R H Janssen

Publications and source records attributed to R H Janssen.

6 recordsLinked to original sources

Role of Megasphaera elsdenii in the Fermentation of dl-[2-C]lactate in the Rumen of Dairy Cattle.

Since Megasphaera elsdenii ferments a variable part of dl-lactate to butyrate, measurement of the percentage of dl-lactate fermented to propionate via the acrylate pathway in rumen contents will underestimate the participation of M. elsdenii in the dl-lactate fermentation. The percentage of dl-[2-C]lactate fermented via the acrylate pathway and the percentage of dl-lactate fermented to butyrate can be measured with C-FT (Fourier transform)-nuclear magnetic resonance. On the average, the contribution of M. elsdenii to dl-lactate fermentation in the rumen of dairy cattle was found to be 74% (standard deviation, 13%), but differed with animal or diet. After feeding a cow readily fermentable carbohydrates, the contribution of M. elsdenii to the fermentation of dl-lactate increased as a consequence of catabolite repression in other dl-lactate-fermenting bacteria.

Journal Article↗

The effects of a depressant and a stimulant drug on the contingent negative variation.

Three groups, each comprising eight subjects, were twice tested with an interval of one week: one group receiving 10 and 20 mg chlordiazepoxide, another group receiving 150 and 300 mg caffeine and a control group receiving placebo and 'no-drug' treatment. During each session the CNV was determined five times: one pre-drug and four post-drug measurements, each divided in a condition with and one without 'white noise'. Based on Eysenck's theory it was predicted that the CNV would increase after administering chlordiazepoxide and would decrease after administering caffeine. Furthermore it was expected that 'white noise' would attenuate the CNV of introverts and would enhance the CNV of extraverts. The first hypothesis was significantly verified comparing the chlordiazepoxide group with the caffeine group. However, making comparisons within groups, only the decrease between the measurement before taking caffeine and the first one after administering was significant. The second hypothesis could be supported for introverts only.

Acoustic Stimulation↗