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Biomedical subjects

R H Lane

Publications and source records attributed to R H Lane.

At least 37 records · Page 2Linked to original sources
PubMed1980

Irradiation injury to large arteries.

Four cases of irradiation injury to large arteries are presented and the literature is reviewed. Three patterns of injury have emerged. 1. Intimal damage resulting in mural thrombosis presenting within 5 years of irradiation. 2. Fibrotic occlusion presenting within 10 years of injury. 3. A predisposition to the development of atheroma together with periarterial fibrosis associated with a latent interval of 20 or more years. The treatment of choice is a bypass procedure of the arterial lesion.

Adult↗
PubMed1977

Idiopathic megacolon: a review of 42 cases.

Forty-two patients with idiopathic megacolon who were seen at St Mark's Hospital over an 18-year period are reviewed with regard to presentation, investigation and management. The differential diagnosis is discussed with particular reference to Hirschsprung's disease. The important aspects of medical treatment are outlined and the possible reasons for failure in more than one-half of the patients are discussed. The indications for surgical intervention in 14 patients are reviewed. The results following subtotal colectomy were better than following a localized sigmoid resection.

Adolescent↗
PubMed1977

Function of the anal sphincters following colo-anal anastomosis.

Developments in sphincter-saving operations for carcinoma of the rectum have led to renewed interest in the function of the pelvic floor muscles and the anal sphincters. Twelve patients with a colo-anal anastomosis have been investigated physiologically with reference to sphincter function. It has been shown that the rectum is not essential for the appreciation of impending evacuation, nor for the sphincter inhibitory reflexes, which in this study were elicited by balloon distension above the anastomosis.

Adult↗