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Biomedical subjects

R H Schosser

Publications and source records attributed to R H Schosser.

17 recordsLinked to original sources

Chronic ulcerative stomatitis associated with stratified epithelial specific antinuclear antibodies. A case report of a newly described disease entity.

A case of erosive oral lesions associated with an unusual direct and indirect immunofluorescent pattern is presented. Rather than a submucosal band or intramucosal intercellular deposition, the pattern is that of an antinuclear antibody that reacts only with stratified epithelium. The clinical similarity of this case to erosive lichen planus is discussed. The usefulness of direct and indirect immunofluorescence techniques in the diagnosis of erosive oral lesions is stressed.

Aged

Squamous cell carcinoma of the scrotum.

A patient with psoriasis was found to have a large mass on his scrotum. He was at increased risk for the occurrence of skin cancer, both from the treatments he received for control of his psoriasis and from previous occupational exposure. We present his case and review the risk factors involved.

Aged

Magnolia grandiflora dermatitis.

A patient is described who had allergies to several sesquiterpene lactone-containing plants, but the reaction to Magnolia grandiflora was extremely severe. The condition was a chronic lichenified dermatitis that was unresponsive to treatment but cleared with protective measures. Primary allergy to Magnolia is rarely reported, even though some studies of cross-reactivity suggest that sensitivity is far from rare.

Clobetasol

Congenital pigmented and vascular lesions in newborn infants.

The incidence of congenital cutaneous lesions was ascertained by a single dermatologist in each of 830 sequential newborn infants over a 3-month period at the Oklahoma Teaching Hospitals. Lesions were observed in 57% of infants (77% of blacks and 49% of nonblacks). Vascular lesions were the most frequent, occurring in 44% of neonates. Pigmented lesions other than mongolian spots were observed in 15.8% of blacks and in 1.6% of whites. Clinical criteria do not readily distinguish nevus cell nevi from other pigmented lesions. Wood's light examination did not enhance the identification of congenital lesions. Inadequate examination of infants and marked underreporting of congenital lesions in newborn infants are widespread.

Black People

Dermatologic photography.

Particularly for the beginning clinical photographer, the details of contour light, texture light, flat light, and fill lights may be intimidating. A physician-photographer may elect to choose a name brand system that has manual exposure capability. The system should include a ring light (or ring light equivalent) and a point source with a guide number of at least 80 (feet with ISO 100 film). Standard exposures may be determined, as has been described above. The ring light should be used for reproduction ratios between 1:1 and 1:20; the point source is saved for ratios of 1:20 and below. As confidence and skill increase, the photographer may choose to use additional light sources, facilitating more subtle forms of lighting. Criteria for choosing equipment have been examined in great detail. The importance of using standardized manual strobe lighting at set reproduction ratios as opposed to automated systems using through the lens flash metering has been stressed. Flat, contour, and texture lighting with techniques to decrease shadow density was also addressed at length. Standard views of body areas, lesion photography, and image storage methods were discussed as well.

Dermatology

Becker's melanosis and hypoplasia of the breast and pectoralis major muscle.

Becker's melanosis can be associated with hypoplastic abnormalities. In our patient (the first case report), it occurred in association with an absent pectoralis major muscle. Although more common in males, this patient demonstrates that Becker's melanosis can occur in females and may be congenital.

Adolescent

Unilateral keratosis follicularis.

Unilateral keratosis follicularis is considered a localized variant of Darier's disease and should be included in the differential diagnosis of zosteriform keratotic eruptions. The authors present a case report and review the treatment; topical retinoic acid appears to be the treatment of choice.

Adult

Muir-Torre syndrome: report of a case and reevaluation of the dermatopathologic features.

Muir-Torre syndrome patients have multiple internal malignancies along with cutaneous sebaceous proliferations and keratoacanthomas. We describe a 62-year-old male with nine primarily internal malignancies who survived eight years after his initial tumor was identified. His sebaceous lesions ranged from innocuous adenomas to an anaplastic carcinoma of the chin which recurred and spread locally to involve the mandible and the right parotid region.

Humans

Cutaneous horns: a histopathologic study.

We report a series of 230 cutaneous horns, of which fewer than one fourth were frankly malignant. Actinic keratoses were the lesions most commonly found underlying cutaneous horns (37.39%). Cutaneous horns overlying a benign lichenoid keratosis, epidermolytic hyperkeratosis, trichilemmoma, an epidermal inclusion cyst, and a benign fibroma are reported. Three cases were nondiagnosable because of inadequate biopsies that were too superficial to show the base of the lesion.

Carcinoma, Squamous Cell