Biomedical subjects
R H Smiley
Publications and source records attributed to R H Smiley.
Estimating the cost of health insurance programs.
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Lactate dehydrogenase from autotrophic and heterotrophic cells of the marine diatom Cylindrotheca fusiformis Reimann & Lewin.
Cultures of Cylindrotheca furisormis grown either autotrohpically or heterotrophically on lactate contained significant amounts of NAD-dependent L(+)-lactate dehydrogenase (EC 1.1.1.27). Polyacylamide gel electrophoresis of crude enzyme extracts revealed a single band which was indistinguishable between autotrohpic and heterotrohpic cells. The Km for lactate of partially purified preparations was lower under heterotrophic conditions. The specific activity in crude extracts was higher under autotrophic than heterotrophic conditions; it dropped precipitously when autotrophic cells were transferred to the dark, increasing again only in the presence of lactate. These and related observations suggest that this enzyme has at most only a minor role in the assimilation of lactate during heterotrophic growth on lactate.
Comparison of femoral artery, femoral vein, and total hind limb blood flow in dogs.
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Experimental basis for the avoidance of vasopressors during heart block.
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Successful treatment of a fulminant hypertensive crisis after bilateral carotid sinus denervation.
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Pulmonary vascular changes in lung lobes with reversed pulmonary blood flow.
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Spontaneous hematomata of the calf.
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