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Biomedical subjects

R H Teske

Publications and source records attributed to R H Teske.

30 records · Page 2Linked to original sources
PubMed1976

Herd health status of animals exposed to polybrominated biphenyls (PBB).

The health status of 16 herds of dairly cattle exposed to low levels of polybrominated bipenyl (PBB) was compared with that of 15 control herds. Milk production of the contaminated herds was not significantly changed in 1972, 1973, and 1974 and was not significantly different from that of control herds in the same years. Mortality of adult cows and calves, the percentages of cows culled from the herds because of old age and low production, disease, or sterility, and the general health conditions were similar in the two groups. Serum concentrations of calcium, glucose, and cholesterol in contaminated herds were significantly different from those of the control herds, but the relationship to PBB exposure needs further investigation.

Animal Feed↗
PubMed1970

Pulmonary absorption and retention of kanamycin after repeated inhalation administration of kanamycin aerosol.

The absorption and retention of kanamycin by the pulmonary system was evaluated after aerosol administration to rats. Tissue level concentrations of the drug were assayed by the agar-plate bioassay method. Mean concentrations of 6.58 mug/g and 3.52 mug/g were found in the lung and kidney homogenates, respectively, 26 hr after the final exposure period. No detectable level was found in the plasma.

Absorption↗
PubMedDate not supplied

Neuromuscular blocking effects of aminoglycoside antibiotics on fast- and slow-contracting muscles of the cat.

The neuromuscular-blocking effects of neomycin, streptomycin, and gentamicin were examined in fast- and slow-twitch muscles of pentobarbital-anesthetized cats. These antibiotics were more effective in reducing indirectly stimulated contractions of the gastrocnemius muscle than of the ipsilateral soleus muscle in adult cats. Respiratory-depressant effects of these antibiotics were more closely associated temporally with effects on soleus than on gastrocnemius twitch. Neomycin was a more potent neuromuscular blocking agent in kittens greater than 7 weeks old than in kittens less than 6 weeks old. Calcium ions were more effective in antagonizing the effects of neomycin on gastrocnemius than on soleus twitch; however, neostigmine was more effective in antagonizing the effects of neomycin on soleus than on gastrocnemius twitch. These data indicate a difference in responsiveness of fast- and slow-twitch muscles (fast greater than slow) to the neuromuscular-blocking effects of aminoglycoside antibiotics, and suggest that this may be related to a difference in the predominance of pre- and postjunctional inhibitory actions of these agents in the 2 muscle types.

Aminoglycosides↗