Prevention of vesicoureteric reflux by endoscopic injection.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to R H Whitaker.
Explore the source record for details and available documents.
The results of 12 years' experience in the surgical treatment of hypospadias fistula are presented. Overall, there was a success rate of approximately 50% for each attempt at surgical closure of a fistula. The chances of success were not significantly influenced by the number of previous surgical procedures. The best results were obtained with fistulae on the shaft of the penis which were closed with mucosal inversion and advancement of a skin flap over the fistula.
Explore the source record for details and available documents.
A total of 1209 undescended testes in 961 boys who had no previous surgery for this problem have been reviewed with particular regard to the outcome of surgery in relation to the pre-operative and intra-operative assessment of the position of the testis. A third of impalpable testes were found at operation in the abdomen, a third in the inguinal canal and a quarter in the superficial inguinal pouch; 1% of all testes and 7% of impalpable testes were absent; 96% of all testes reached the scrotum at operation and this figure included 69% of abdominal and 94% of canalicular testes. In all 24 testes were excised--7 of which were abdominal, 8 canalicular and 9 were in the superficial inguinal pouch. The generalisation that the higher the undescended testis before operation the poorer the result, does not always hold true.
Major urological trauma is life threatening and frequently associated with trauma to other organs. A conservative approach to lesser degrees of damage to the kidney is fully justified whilst a shattered kidney or a pedicle injury calls for surgical exploration. Renal injuries between these two extremes require careful assessment and clinical judgement to decide the best management. An intravenous urogram remains the mainstay of investigation but computed tomography, ultrasound and arteriography can be useful in some circumstances. The management of urethral trauma remains controversial and depends largely on the assessment of whether the posterior urethra is partially or completely ruptured. There remain two schools of thought concerning early or late intervention but all are agreed that suprapubic diversion is essential and that a urethral catheter should not be passed blindly in the initial stages. A ruptured bladder should always be repaired and early intervention is recommended for ureteric injuries. Severe trauma to the testis is best managed operatively to reduce the morbidity.
The Deavin-Hunt device is designed to help paraplegic and incontinent women to catheterise themselves whilst in a wheelchair. Such patients with neuropathic bladder might otherwise be unable to use intermittent catheterisation, an effective method of controlling incontinence and preserving the kidneys.
Explore the source record for details and available documents.
There is variable virilisation in female pseudohermaphrodities with congenital adrenal hyperplasia, but they always have normal ovaries, uterus and upper part of the vagina. The various anatomical stages of virilisation are outlined and a historical review is given. For psychological and practical reasons it is generally accepted that the operation should be performed when the patient is between 6 and 18 months of age. The aim is to reduce the size of the clitoris and to expose the vagina so that it opens onto the perineum. Operative procedures are described. The child is reviewed at intervals to determine the size and shape of the vagina and clitoris. Adjustments can be made around the time of puberty but are rarely necessary.
Explore the source record for details and available documents.
A group of 309 children over the age of 2 years was investigated with ultrasound and plain X-ray for suspected urinary infection. In 29 cases there were abnormal findings and in 10 the abnormalities were confirmed with cystography and intravenous urography. Of 280 children whose ultrasound and plain X-ray findings were normal, 26 re-presented with further symptoms and investigation with cystography and urography showed abnormalities in only 4. The remaining 254 children have remained well and have been spared the uncomfortable and potentially dangerous examinations of cystography and urography.
Despite advances in radiological imaging techniques, the ideal management of antenatally diagnosed hydronephrosis remains controversial. A map, showing diagnostic and management pathways, has been designed in an attempt to provide maximum information from the most appropriate and minimum number of investigations.
Explore the source record for details and available documents.
An insulated diathermy hook was used to destroy the posterior urethral valve in 10 boys. The technique needs no anaesthetic, no endoscopic equipment, no perineal urethrostomy and only occasional catheter drainage of the bladder. It is performed in the X-ray department, where the efficacy of the procedure can be checked immediately with a further cystogram. The results are compared with those in 7 other boys whose valves were destroyed by conventional endoscopic means.
Explore the source record for details and available documents.
A total of 216 patients with voiding disorders were treated with oxybutynin and the effects and side effects were studied. The drug is effective in a wide variety of disorders. Good results were obtained in 66% of patients who had no previous treatment and in 46% of patients who had taken various drugs before. It was just as effective in all age groups. Twenty-three per cent of patients experienced side effects and 10% were unable to tolerate the drug. It is concluded that oxybutynin is an effective drug in the treatment of unstable bladder and disorders such as catheter-induced spasms.
In 190 patients with neural tube defects the sensory levels to pin prick were compared with the incidence and distribution of congenital renal anomalies. 17 such anomalies comprised 3 examples of renal agenesis, 5 horseshoe kidneys, 8 ureteral duplications and one simple ureterocele. The pattern of anomalies showed that renal agenesis was associated with a sensory level in the dermatomes T5-8, horseshoe kidneys with T9-L1 and duplications predominantly with the sacral dermatomes.
The hypothesis that undescended testis is caused by an excess of maternal oestrogen in pregnancy has been tested indirectly in a case-control study comparing mothers of boys with undescended testis (83) and mothers of normal boys (129) born on the same day. The study concentrated on the gestation of the boys, but also investigated the mother's previous obstetric history and postnatal events in the boys. The hypothesis predicted that there should be an excess of nausea, vomiting and hypertension in mothers of cases, but in fact the pregnancies of the case and control mothers were similar in all respects except one. The exception was the increased liability of the mothers of cases to threatened abortion. Mothers of cases also had an increased tendency to miscarry in previous conceptions, a reduced number of deliberate terminations and evidence of decreased fertility. An alternative hypothesis is suggested which would explain these findings. This is that placental function is impaired in the gestation of affected boys and the secretion of human chorionic gonadotrophin is reduced. This leads to changes in fetal testicular function and possible maldescent. Those born with undescended testis were more likely to present to a general practitioner with illness in the first three years after birth and this difference was mainly due to asthma, eczema, jaundice and feeding difficulties.