Biomedical subjects
R Hara
Publications and source records attributed to R Hara.
Regeneration of squid retinochrome.
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Rhodopsin and retinochrome in the octopus retina.
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Rhodopsin and retinochrome in the squid retina.
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[20 Years of pediatric nursing at the Kiyose Children's Hospital, Tokyo].
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[Recent trends in childhood tuberculosis].
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New photosensitive pigment found in the retina of the squid Ommastrephes.
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Postoperative radiation therapy for stage IB-IIB carcinoma of the cervix with poor prognostic factors.
BACKGROUND: To investigate failure pattern and to evaluate the prognostic impact of lymph node metastasis in patients with cervical cancer treated with postoperative adjuvant pelvic irradiation. MATERIALS AND METHODS: Ninety-eight patients with FIGO IB to IIB cervical cancer were treated with radical hysterectomy, bilateral pelvic lymphadenectomy and postoperative radiation therapy. All the patients had at least one of the following pathologic risk factors for pelvic recurrence; 1) positive margins, 2) positive pelvic lymph nodes other than common iliac node, 3) deep stromal invasion more than 50% or parametrial invasion. RESULTS: The 5-year overall survival (OAS) rate for the entire patient group was 82%. Causes of the first failure were pelvic recurrence in 5 cases and distant metastasis in 15 cases. Fifteen of the 47 patients with positive pelvic lymph nodes developed distant metastasis, whereas distant metastasis was noted in only 1 of 51 patients without lymph node metastasis. The 5-year OAS rates for patients with and without pelvic lymph node metastasis were 76% and 89%, respectively (p = 0.018). CONCLUSION: Despite receiving postoperative pelvic irradiation, apparently lower survival was observed for node positive patients.