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Biomedical subjects

R Hennekes

Publications and source records attributed to R Hennekes.

At least 19 recordsLinked to original sources

Diplopia as an initial manifestation of disseminated non-hodgkin's lymphoma.

A 37-year-old male presented a sudden diplopia. Ocular examination showed a partial paresis of the left eye (LE) on the left gaze, progressing in a few days towards a total ophthalmoplegia. Further investigation revealed an intra-orbital mass, immunohistologically diagnosed as a Diffuse Large B-cell Lymphoma (DLBCL), according to the WHO classification. Since the patient was in an advanced, disseminated stage of the disease (IVA-E), treatment was based on systemic and intrathecal chemotherapy with a pancranial radiotherapy. The clinical course was poor with only a 10-month survival. We wish to stress that the possibility of orbital malignancy in young adults with acute onset of ophthalmoplegia should be included in the differential diagnosis.

Adult↗

Long-term results of wagon wheel packed acrylic intra-ocular lenses (AcrySof).

To evaluate long-term results of Wagon Wheel packed AcrySof intraocular lenses (IOLs), 88 and 39 patients (115 and 55 eyes respectively) were examined at 14 and 28 months respectively. Visual acuity increased from an average of 0.324 preoperatively to about 0.722 one week post-operatively. A YAG capsulotomy had to be performed in two eyes only. Vacuoles, as described with the Acry Pak system, were also detectable in our Wagon Wheel packed lenses. They increased significantly in incidence and number with time.

Aged↗

Medium term results of HEMA intraocular lenses (Hydroview).

A group of 232 eyes that received a HEMA IOL (Hydroview, Storz Inc.) was followed over a period of six months. Mean visual acuity increased from 0.41 preoperatively to 0.79 post-operatively. During the follow-up period, the visual acuity remained stable in 175 eyes and decreased in 57 eyes, mainly due to progression of ARMD and posterior capsule opacification (PCO). Nine eyes required YAG-laser capsulotomy. Cell migration on the anterior surface of the Hydroview IOL was observed in 100% of the cases after a period of 3 months.

Adult↗

Cyclocryocoagulation vs. trabeculectomy in primary glaucoma: a long-term intra-individual comparison of intra-ocular pressure.

This study compares long-term efficacy (up to 48 months) of cyclocryocoagulation and trabeculectomy in lowering the intraocular pressure (IOP). Intraocular pressure evolution after cyclocryocoagulation in one eye and trabeculectomy in the fellow eye for the treatment of primary open- and narrow-angle glaucoma was monitored in five patients. After 4 years both interventions were still active. Cyclocryocoagulation was slightly less effective in lowering IOP but associated with considerably less complications than trabeculectomy.

Aged↗

[Asymmetric corneal tunnel incision for routine phacoemulsification and lens implantation].

UNLABELLED: This study was designed to investigate whether it is possible to improve wound stability and reduce induced astigmatism of a linear corneal tunnel incision for the implantation of foldable intraocular lenses by radializing wound components. MATERIALS AND METHODS: A 4.1-mm linear and a 2.5 x 2.5-mm L-shaped corneal tunnel incision were compared in 60 and 59 patients, respectively. RESULTS: Complications and induced astigmatism (vector analysis) were significantly less in the L-shaped incision group than in the linear incision group (0.62 +/- 0.53 D vs. 0.84 +/- 0.75 D after 3 months). CONCLUSION: An L-shaped incision seems to be superior to the conventional linear type.

Astigmatism↗

Astigmatic change after myopic spherical excimer PRK.

85 Patients who underwent a spherical PRK with an average of 6.08 dptr. and who could be followed over a period of 1 year were evaluated. After 1 year an average induced astigmatism of 0.58 dptr. was found. There seems to be a correlation between induced astigmatism and depth of PRK but not between induced astigmatism and pre-existent astigmatism. In cases of decentrated PRK a spontaneous regression of laser-induced astigmatism could be observed.

Adult↗

A high-stability, one-stitch W incision for cataract surgery.

We describe a technique to create a highly stable, one-stitch incision for use with rigid posterior chamber intraocular lenses (IOLs). Inverse U and W incisions are compared in 203 consecutive eyes with 3 months follow-up. A scleral groove resembling an inverted W is dissected away from the limbus, and the anterior chamber is entered by a conventional tunnel technique that resembles a frown incision but has an additional triangular, central scleral flap. When the incision is closed, a single stitch is placed through the flap, away from the limbus. Advantages of the W incision include reduction and control of astigmatism, improved self-sealing, reduced postoperative leakage, no special suture-material requirements, high mechanical stability, easy extendability for extracapsular cataract extraction or trabeculectomy, and intraoperative sealing of a leaking irrigation/aspiration opening by inverting the flap. The W incision offers high stability and multiple advantages over the frown incision and is suitable for use with rigid posterior chamber IOLs.

Astigmatism↗

Implantation of posterior chamber lenses of more than 30 dptr.

Posterior chamber lenses of more than 30 dptr. are supposed to correct preexisting high hyperopia. With high diopters, however, problems emerge which are not to be found in eyes requiring lower lens powers. These problems are neurosensory disorders, residual accommodation, difficulties in power calculation, unavailability of appropriate lenses and thick lens optics. These difficulties and possible solutions are addressed referring to cases of IOL powers between 46 and 53 dptr.

Aged↗

Posterior chamber lens implantation in children and infants.

Today the implantation of posterior chamber lenses in children and infants is still controversial. We report on the results of posterior chamber lens (PCL) implantation in a series of children with unilateral cataract, aged between 6 months and 14 years.

Adolescent↗

Vectoranalysis of surgically induced astigmatism in small corneal and scleral cataract incisions.

Vector analysis of surgically induced astigmatism was performed on several scleral and corneal tunnel incisions (6.0-mm W; 3.5- and 2.5-mm L scleral tunnel; 4.1-mm linear and 2.5-mm L corneal tunnel). The analysis revealed a mean astigmatism between 1.18 and 0.64 D, as compared to 0.35 D in a control group of nonoperated eyes. The best results were obtained with the scleral and corneal L-shaped incisions.

Astigmatism↗

I-123-IDAB: a new tracer for scintigraphic visualisation of malignant melanoma.

I-123-N-(2-Diethylaminoethyl) 4-lodobenzamide (I-123IDAB) has recently been introduced as a radiopharmaceutical agent in the management of patients with malignant melanoma. We tested the diagnostic potential of this substance in 5 patients suspected of having an ocular malignant melanoma. I-123-IDAB scintigraphy identified 4 patients with high tracer uptake in the pathologic eye. Three cases were confirmed histologic as a malignant melanoma, the fourth patient was submitted to radiotherapy. The amelanotic (histologically confirmed) irismelanoma of the fifth patient could not be detected. From these preliminary results we conclude that I-123-IDAB scintigraphy may be a valuable tool for establishing the diagnosis of malignant melanotic melanoma.

Aged↗

Stray light in photorefractive keratectomy for myopia.

We performed a study to evaluate the influence on visual function of intraocular straylight after photorefractive keratectomy (PRK). We present 4 eyes of 4 myopic individuals, who had contacted our clinic for keratorefractive surgical treatment. PRK's were performed with a Summit laser, using a 5 mm ablation zone. The straylight meter was used to measure the amount of intraocular scattered light, the physical cause of glare complaints, before and after PRK. This apparatus uses the direct compensation method to assess the amount of intraocular light scatter. The results showed a significant increase in straylight values, in the tested eyes, during the first two weeks after PRK. After the initial rise, straylight values returned to preoperative levels, except for two eyes that clearly developed a haze higher than grade two. Instead of returning to baseline levels, straylight values remained significantly higher in these eyes.

Adult↗

W incision for combined cataract and glaucoma surgery.

The W incision can be regarded as a self sealing incision with an additional posterior flap. For cataract surgery, the flap can be used to add further stability to the incision whilst for combined glaucoma surgery it can also be used to "cover" a trabeculectomy located underneath. Up to now, 14 eyes underwent a combined cataract and glaucoma surgery using the W incision. In this article the short term postoperative results and advantages of this new technique in combined cataract and glaucoma surgery are discussed.

Aged↗

W incision for cataract surgery.

We suggest a modification of the frown type incision for the implantation of rigid intraocular lenses: a W shaped incision. It has improved the control of astigmatism, the self sealing characteristics, needs no special requirement for suture material, has a high mechanical stability, and is easily extendible for ECCE or trabeculectomy. The advantages of the incision are substantiated in a comparative study (invers u and W configuration) in 203 eyes with a 3 months follow up.

Cataract Extraction↗

Transsclerally sulcus fixated anterior chamber lenses in eyes without posterior capsule support: three years follow up.

Three years ago we started to implant commercially available anterior chamber lenses with S-shaped haptics an multipoint support into the posterior chamber in cases of secundary lensimplantation after intracapsular cataract operation. The lenses were transsclerally fixed by two sutures through the ciliry sulcus. They exhibit more stability than the C-loop posterior chamber lens and induce some scar formation possibly enabling them to stay firm even after degradation of the suture.

Anterior Chamber↗

Differentiated treatment of secondary cataract following extracapsular cataract operation.

161 eyes with Nd:YAG laser posterior capsulotomy after in the bag IOL implantation 1-3 years before, were actively followed over a period of 24 +/- 6 months. No CME nor retinal detachment nor induced glaucoma was found. Therefore a YAG capsulotomy in eyes with completely in the bag implanted IOL seems to assure the same level of security than capsular polishing in eyes with sulcus implanted lenses.

Adult↗

Probing and silicone intubation of the lacrimal system in adults.

We evaluated an atraumatic catheterisation of the lacrimal system in 23 cases under local anaesthesia in adults. By using this method 60% of the eyes with canaliculus stenosis and about 40% of the eyes with inferior lacrimal duct stenosis could be treated successfully. We suggest that lacrimal duct catheterisation under local anaesthesia can be used as a substitute for DCR in selected cases especially in elderly patients giving a good chance of cure without invasive operation.

Adolescent↗

Phacoemulsification of the subluxated or atopic lens.

In cases of an ectopic lens (e.g. Marfan Syndrome) with elongated zonular fibers, the lens can be partially emulsified. This can be done in such a way that it leaves behind a diaphragm consisting of zonular fibers and posterior capsule which is strong enough to support a posterior chamber lens. In cases of traumatically subluxated lenses intercapsular phacoemulsification can be done. The zonular dialysis can be fixed by suturing the capsule directly into the sulcus. The PCL can then be implanted either into the capsular bag or into the sulcus. Suture fixation of a posterior capsule is also possible as a reconstructive measure in previously extracapsular operated eyes.

Adult↗